Molecular biology of Alzheimer's disease : genes and mechanisms involved in amyloid generation
著者
書誌事項
Molecular biology of Alzheimer's disease : genes and mechanisms involved in amyloid generation
Harwood Academic Publishers, c1998
大学図書館所蔵 全8件
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, risk factors such as ApoE, and transgenic animal models. Some of the latest developments in Alzheimer's disease research, including the effect of presenilin knock outs on amyloid -peptide generation, are also included.
目次
1. The Tau Proteins in Alzheimer's Disease 2. The Genetics of Familial Alzheimer's Disease 3. Mutations in Three Genes Are Associated with Early Onset Alzheimer's Disease 4. The Molecular Biology of Presenilin 1 5. Molecular Biology of Presenilin 2 6. Presenilin Proteins and Their Role in Development and Notch Signaling 7. Transgenic Animal Models in the Development of Therapeutic Strategies for Alzheimer's Disease 8. Amyloid Morphology and Pathology of Alzheimer's Disease 9. The Biological Activities and Function of the Amyloid Precursor Protein of Alzheimer's Disease 10. Transgenic Models of Alzheimer's Disease
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