Clinical trials in cardiovascular disease : a companion to Braunwald's heart disease
著者
書誌事項
Clinical trials in cardiovascular disease : a companion to Braunwald's heart disease
W.B. Saunders, c1999
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内容説明・目次
内容説明
This state of the art companion to Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 5th Edition is the first resource to review all the current knowledge in cardiovascular disease medicine derived from clinical trials. It examines current issues in clinical trial methods - as well as the latest findings on the effectiveness of specific treatment and prevention strategies. Written by leading experts in cardiovascular disease, this new book offers indispensable guidance for clinical decision-making in all patient care settings.
目次
Part I: Methodology. Contribution of Basic Research, Observational Epidemiology and Randomized Trials. Methodology of Randomized Trials. Special Features of Primary Prevention Vs. High-Risk Vs. Secondary Prevention Trials. Strengths and Limitations of Large, Simple Trials Vs. Small Trials. Principles of Data Monitoring Boards in Trials. Meta-Analysis. Part Ii: Treatment Trials. Aspirin and Heparin. Thrombolytic Therapy. Beta-Blockers. Ace Inhibitors. Calcium Channel Blockers. Magnesium. Nitrates. Direct Thrombin Inhibitors. Glycoprotein Iib/Iiia Receptor Inhibitors. Primary and Rescue Angioplasty. Lipid-Lowering Agents. Anti-Arrhythmia Therapy in Ischemic Heart Disease. Anti-Arrhythmia Therapy in Atrial Fibrillation. Anti-Platelet Agents and Anticoagulation in Ischemic Heart Disease. Anti-Platelet Agents and Anticoagulation in Atrial Fibrillation. Angioplasty and Bypass Surgery. Exercise. Congestive Heart Failure. Part Iii: Prevention Trials: Cholesterol Reduction. Blood Pressure Reduction. Smoking Cessation. Weight Reduction/Exercise. Stress Reduction. Aspirin Prophylaxis. Postmenopausal Hormone Replacement Therapy. Antioxidant Vitamins. Other Dietary Interventions. Multiple Risk Factor Intervention Trials. Prevention Strategies: Population-Based, Community-Based, Worksite, Targeted High Risk Subgroups. Part Iv: Future Needs.
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