Applied biopharmaceutics & pharmacokinetics

Bibliographic Information

Applied biopharmaceutics & pharmacokinetics

Leon Shargel, Andrew Yu

Prentice-Hall International, c1999

4th ed., International ed

Other Title

Applied biopharmaceutics and pharmacokinetics

Available at  / 11 libraries

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Note

On spine: Appleton & Lange

Includes bibliographical references and index

Description and Table of Contents

Description

This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.

Table of Contents

  • Mathematical fundamentals on pharmacokinetics
  • introduction to biopharmaceutics and pharmacokinetics
  • one compartment model
  • physiological factors relating to drug absorption
  • biopharmaceutic considerations in drug product design
  • modified release drug products
  • delivery of biotechnical products and targetted drug delivery systems
  • pharmacokinetics of drug absorption
  • bioavailability and bioequivalence
  • multicompartmental models
  • drug distribution and protein binding
  • drug clearance
  • drug metabolism and hepatic clearance
  • pharmacokinetics after intravenous infusion
  • pharmacokinetics after multiple dosing
  • non-linear pharmacokinetics
  • introduction to clinical pharmacokinetics
  • application of pharmacokinetics to clinical situations
  • relationship between pharmacokinetic parameters and pharmacologic response
  • physiologic pharmacokinetic model and statistical moment
  • computer applications in pharmacokinetics
  • biopharmaceutics and pharmacokinetic studies in drug development
  • appendix.

by "Nielsen BookData"

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