Pharmaceutical excipients : characterization by IR, Raman, and NMR spectroscopy

Author(s)

• Bugay, David E.
• Findlay, W. Paul

Bibliographic Information

Pharmaceutical excipients : characterization by IR, Raman, and NMR spectroscopy

David E. Bugay, W. Paul Findlay

（Drugs and the pharmaceutical sciences, v. 94）

M. Dekker, c1999

• hbk.

Note

Includes index

Description and Table of Contents

Description

Meeting the need for a hands-on guide elucidating the role of molecular spectroscopy in the physical characterization of pharmaceutical solids, two experts from the industry gather theoretical discussions of infrared, Raman, and nuclear magnetic resonance spectroscopy. They provide recommendations on spectral data acquisition techniques and include 600 spectra for 300 of the most commonly used excipients. Complete with references, equations, tables, and a CAS registry number index, the book covers the drug development process, including chemical identification of substances, investigative studies, competitor analysis, problem solving activities, reproduction of spectral data, and more.

Table of Contents

Vibrational Spectroscopy Nuclear Magnetic Resonance Spectroscopy Experimental Excipients Acacia Acetic Acid Acetone Acetyltributyl Citrate Acetyltriethyl Citrate Acrylamide/Sodium Acrylate Copolymer, G-400 Acrylic Acid Copolymer Adipic Acid Agar Alcohol Alginic Acid d-Alpha Tocopheryl Polyethylene Glycol 1000 Succinate Ammonium Acetate Ammonium Phosphate Dibasic trans-Anethole Apricot Kernel Oil PEG-6 Esters Ascorbic Acid Ascorbyl Palmitate Aspartame L-Aspartic Acid Benzaldehyde Benzalkonium Chloride Benzethonium Chloride Benzoic Acid Benzophenone Benzyl Alcohol Benzyl Benzoate Boric Acid Butyl Alcohol n-Butylamine Butylated Hydroxyanisole Butylated Hydroxytoluene Caffeine Calcium Acetate, Monohydrate Calcium Carbonate Calcium Phosphate Dibasic, Dihydrate Calcium Phosphate Tribasic Calcium Silicate Calcium Sulfate Calcium Sulfate, Dihydrate Carbomer, 934P Carbopol, 1342 NF Resin Carboxymethylcellulose Sodium Carrageenan Castor Oil Cellulose, Microcrystalline 50M Cellulose, Microcrystalline 90M Cellulose, Microcrystalline Ph102 Cellulose, Microcrystalline Ph200 Cellulose Acetate Phthalate Cellulose Acetate Trimellitate/Trimellitic Acid Cetrimide Cetyl Alcohol Cetylpyridinium Chloride, Anhydrous Chloroform Cholesterol Citric Acid, Anhydrous Citric Acid, Monohydrate Corn Oil PEG-6 Esters Corn Starch, B700 Corn Starch, B810 Corn Starch, B880 Corn Starch, B890 Corn Starch Acrylamide Sodium Acrylate Copolymer, A-140 Corn Starch Acrylamide Sodium Acrylate Copolymer, A-222 Corn Starch Acrylamide Sodium Acrylate Copolymer, D-212 Corn Syrup Solids, M200 Corn Syrup Solids, M250 Corn Syrup Solids, M365 Cottonseed Oil Croscarmellose Sodium Crospovidone B-Cyclodextrin D&C Red # 27 Lake D&C Yellow #10 Lake Denatonium Benzoate Dextrates Dextrin Diacetylated Monoglyceride, 9-40 Dibutyl Phthalate Dibutyl Sebacate, NF Dichloromethane Diethyl Phthalate, NF Diethylene Glycol Monoethyl Ether Dimethicone, NF 20 Dimethyl Sulfoxide Dioctyl Phthalate Docusate Sodium Edetate Disodium, Dihydrate Ethyl Acetate Ethyl Maltol Ethylcellulose, Medium, Viscosity=50 Ethylcellulose, Medium, Viscosity=70 Ethylcellulose, Standard, Viscosity=4 Ethylcellulose, Standard, Viscosity=10 Ethylcellulose, Standard, Viscosity=100 Ethylparaben FD&C Blue #2 Lake FD&C Blue #2 Powder FD&C Red #3 Powder FD&C Red #40 Lake FD&C Red #40 Powder FD&C Yellow #5 Lake FD&C Yellow #5 Powder FD&C Yellow #6 Lake FD&C Yellow #6 Powder D-Fructose Fumaric Acid Gelatin Gentisic Acid Ethanolamide Glucose Glycerin Glycerol Mono-/Di-Caprylate/Caprate, 742 Glycerol Stearate, 191 Glyceryl Behenate Glyceryl Caprylate, 988 Glyceryl Cocoate, 928 Glyceryl Laurate, 312 Glyceryl Monooleate, 18-92 Glyceryl Monooleate, 18-99 Glyceryl Palmitostearate Guanine Gum, Guar Gum, Xanthan Hard Fat, AM Hexylene Glycol Hydroxyethyl Cellulose Hydroxypropyl Cellulose Hydroxypropyl Methylcellulose, E3 PREM Hydroxypropyl Methylcellulose, E15LV PREM Hydroxypropyl Methylcellulose, F4 PREM Hydroxypropyl Methylcellulose, K3 PREM Hydroxypropyl Methylcellulose, K100M PREM Hydroxypropyl Methylcellulose, 2208, K15M PREM CR Hydroxypropyl Methylcellulose, 2208, K100M PREM CR Hydroxypropyl Methylcellulose, 2910, E6 PREM Hydroxypropyl Methylcellulose, 2910, E4M PREM CR Hydroxypropyl Methylcellulose, 2910, E10M PREM CR Hydroxypropyl Methylcellulose, Acetate Succinate, AS-LF Hydroxypropyl Methylcellulose, Phthalate, 50 Hydroxypropyl Methylcellulose, Phthalate, 55 Isobutyl Acetate sec-Isopropyl Alcohol Isopropyl Myristate Isopropyl Palmitate Kaolin Lactic Acid Lactose, Anhydrous Lactose, Fast-Flo Lactose, Hydrous Lecithin Ludipress Magnesium Carbonate, Pentahydrate Magnesium Stearate Magnesium Sulfate, Anhydrous DL-Malic Acid Maltitol, MR-20 Maltodextrin, M040 Maltodextrin, M050 Maltodextrin, M100 Maltodextrin, M150 Maltodextrin, M180 Maltol Mannitol, Granular Mannitol, Granular USP 2080 Mannitol, Parenteral Mannitol, Power Meglumine Menthol Methacrylic Acid Copolymer-Methanol Methyl Salicylate Methylcellulose, A4C PREM Methylcellulose, A4M PREM Methylcellulose, A15C PREM Methylcellulose, A15LV PREM Methylparaben Mineral Oil Mineral Oil, Light Monoammonium Glycyrrhizinate, 100 Monoammonium Glycyrrhizinate, 110 Monoammonium Glycyrrhizinate, 180 Monoethanolamine Monothioglycerol Octanoic Acid, Sodium Salt Oleyl Alcohol, NF Opadry, YS-1-2546 Opadry II, Y-22-7719 Opadry Blue, OY-6529 Opadry White, OY-7300 Opadry White, YS-1-7003 Orange Mandarin Orange Terpeneless Paraffin, Flakes Peanut Oil Petrolatum Phenol Poloxamer, 188 Poloxamer, 407 Polyethylene Glycol, 300 NF Polyethylene Glycol, 1000 NF, FCC Polyethylene Glycol, 540 Blend, NF Polyethylene Glycol, 3350 Flake, NF Polyethylene Glycol, 8000 Powder NF, FCC Polyethylene Glycol, Compound 20 M Flake FCC Polyethylene Glycol 8 Caprylic/Capric Glycerides Polyethylene Glycol, 660 12-Hydroxystearate, HS 15 Polyethylene Glycol, 10 Oleyl Ether Polyethylene Oxide, 205 Polyethylene Oxide, 1105 Polyethylene Oxide, N-80 Polyethylene Oxide, N-750 Polyethylene Oxide, N-60000 Polyethylene Oxide, Coagulant Polyglyceryl Oleate, FCC Polyoxyl 35 Castor Oil Polyoxyl 40 Stearate Polysorbate, 20 Polysorbate, 80 Polyvinyl Alcohol, Hydrolyzed Potassium Carbonate Potassium Citrate Potassium Metabisulfite Potassium Phosphate, Monobasic Potassium Sodium Tartrate, Tetrahydrate Potassium Sorbate Povidone Propionic Acid Propylene Carbonate Propylene Glycol Propylene Glycol Laurate, FCC Propylparaben Pyridine Riboflavin Saccharin Saccharin Sodium, Dihydrate Safflower Oil Saturated Polyglycolyzed Glycerides, 44/14 Saturated Polyglycolyzed Glycerides, 50/13 Saturated Polyglycolyzed Glycerides, 53/10 Silicon Dioxide, Colloidal Simethicone, Emulsion LS USP Simethicone, Emulson USP Simethicone, GS Simethicone, USP Sodium Acetate, Anhydrous Sodium Alginate Sodium Ascorbate Sodium Benzoate Sodium Bicarbonate Sodium Borate Sodium Carbonate Sodium Citrate, Dihydrate Sodium Cyclamate Sodium Lauryl Sulfate Sodium Metabisulfite Sodium Phosphate Dibasic, Anhydrous Sodium Phosphate Monobasic, Anhydrous Sodium Propionate, Anhydrous Sodium Starch Glycolate Sodium Stearate Sodium Stearyl Fumarate Sodium Sulfate, Anhydrous Sodium Sulfite Sorbic Acid Sorbitan Monopalmitate Sorbitan Monostearate Sorbitan Trioleate Sorbitan Tristearate Sorbitol Soybean Oil Starch, Fully Pregelatinized 1551 Starch, Partially Pregelatinized 1500 Starch, Partially Pregelatinized 1500LM Stearic Acid Stearyl Alcohol Succinic Acid Sucrose Sucrose Octaacetate Sugar, Confectioner's Sulfanilamide Talc DL-Tartaric Acid Thimerosal Thymol Titanium Dioxide Triacetin Tributyl Citrate Triethanolamine Triethyl Citrate Triton, X-100 Urea Vanillin Vegetable Oil, Hydrogenated Type I Vinyl Acetate Crotonic Acid Copolymer Vinylpyrrolidone-Vinyl Acetate Copolymer, VA64 Water, Purified Wax, Carnauba Wax, Emulsifying Wheat Germ Oil Appendix A: Summary of Characteristic Raman and Infrared Frequencies Appendix B: Representative Chemical Shift Values for NMR Spectroscopy Chemical Abstracts Service Index

by "Nielsen BookData"

Details

• NCID: BA41408424
• ISBN:
  • 0824793730
• LCCN: 98056652
• Country Code: us
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: New York
• Pages/Volumes: xii, 669 p.
• Size: 29 cm
• Classification:
  • LCC : RS201.E87
  • NLM : W1
  • NLM : QV 800
  • DC21 : 615/.19
• Subject Headings:
  • LCSH : Excipients -- Spectra
  • MESH : Excipients -- analysis
  • MESH : Spectrophotometry, Infrared
  • MESH : Spectrum Analysis, Raman
  • MESH : Nuclear Magnetic Resonance
• Parent Bibliography ID:
  • BA03948165