Amiloride-sensitive sodium channels : Physiology and functional diversity
著者
書誌事項
Amiloride-sensitive sodium channels : Physiology and functional diversity
(Current topics in membranes, v. 47)
Academic Press, c1999
- :pbk
大学図書館所蔵 全16件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.
目次
D. Benos, Preface.
Structure-Function Relations of Amiloride-Sensitive Sodium Channels:
C.M. Fuller, I.I. Ismailov, B.K. Berdiev, V.Gh. Shlyonsky, and D.J. Benos, Mapping Structure/Function Relations in alpha-bENaC.
P.M. Snyder, C. Cheng, and M.J. Welsh, Membrane Topology, Subunit Composition, and Stoichiometry of the Epithelial Na+ Channel.
T.R. Kleyman, I. Ismailov, F. Kosari, B.K. Berdiev, J. Li, and S. Sheng, Subunit Stoichiometry of Heteroligomeric and Homoligomeric Epithelial Sodium Channels.
Regulation of Sodium Channels:
N. Farman, S. Djelidi, M. Brouard, B. Escoubet, M. Blot-Chabaud, and J.P. Bonvalet, Cell-Specific Expression of EnaC and its Regulation by Aldosterone and Vasopressin in Kidney and Colon.
D. Rotin, O. Staub, P. Plant, T. Ishikawa, and L. Schild, Regulation of EnaC by Interacting Proteins and by Ubiquitination.
S. Sariban-Sohraby, Role of G-Proteins in the Regulation of Apical Membrane Sodium Permeability by Aldosterone in Epithelia.
J.P. Johnson, J.-M. Wang, and R.S. Edinger, The Role of Post-Translational Modifications in the Cellular Mechanism of Aldosterone.
J.A. Schafer, L. Li, D. Sun, R.G. Morris, and T.W. Wilborn, Regulation of Amiloride-Sensitive Na+ Channels in the Renal Collecting Duct.
P.R. Smith, cAMP Mediated Regulation of Amiloride-Sensitive Sodium Channels: Channel Activation or Channel Recruitment?
J.K. Bubien, Human Lymphocyte Ionic Conductance.
H. Cantiello, Regulatory Aspects of Apx, a Novel Na+ Channel with Connections to the Cytoskeleton.
Sodium Channels in the Lung:
C.R. Talbot, Species Specific Variations in EnaC Expression and Localization in Mammalian Respiratory Epithelium.
S. Matalon, M.D. DuVall, and A. Lazrak, Inhibition of Vectorial Na+ Transport Across Alveolar Epithelial Cells by Nitrogen-Oxygen Reactive Species.
H. O'Brodovich, B. Rafii, A.K. Tanswell, and O. Pitkanen, Induction of Epithelial Sodium Channel Expression and Sodium Transport in Distal Lung Epithelia by Oxygen.
Y. Marunaka and N. Niisato, Catecholamine Regulation of Amiloride-Sensitive Na+ Transport in the Fetal Rat Alveolar Epithelium.
S. Guggino, Cyclic-Nucleotide Gated Cation Channels Contribute to Sodium Absorption in Lung: Role of Non-Selective Cation Channels.
Sensory and Mechanical Transduction:
M. Driscoll, H.A. Thieringer, S. Sahota, and I. Mano, C. elegans Members of the DEG/EnaC Channel Superfamily: Form and Function.
S.C. Kinnamon, B. Lindemann, and T.A. Gilbertson, Amiloride Sensitive Sodium Channels in Taste.
Clinical Relevance:
D. Benos, The Involvement of Amiloride-Sensitive Na+ Channels in Human Genetic Hypertension: Liddle's Syndrome.
I.I. Ismailov and B.K. Berdiev, Epithelial Sodium Channels in Cystic Fibrosis.
「Nielsen BookData」 より