Stereoselectivity in synthesis
著者
書誌事項
Stereoselectivity in synthesis
(A Wiley-Interscience publication)
J. Wiley, c1999
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Many chemicals are found in "right-" and "left-handed" forms that may react differently in the body. In planning a synthesis, chemists must know how to select the best method for making the preferred form of a chemical. This book shows how to choose the best method for a given synthesis. It provides readers with a thorough understanding of stereoselectivity in organic and medicinal chemistry as well as the pharmaceutical, agricultural, and food industries.
目次
Some Fundamental Concepts.
1,2-Stereoinduction.
1,3-Stereoinduction.
Stereoinduction at Long Distances.
Group Directed Reactions and Chelation Effects.
Conformational Effects.
Topographical and Template Effects.
Steric, Electrostatic, and Stereoelectronic Effects.
Thermodynamic Control and Kinetic Trapping.
Index.
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