Monoclonal antibody-based therapy of cancer

書誌事項

Monoclonal antibody-based therapy of cancer

edited by Michael L. Grossbard

(Basic and clinical oncology, 15)

M. Dekker, c1998

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

In light of recent clinical breakthroughs in the field, this lucid book presents up-to-date and comprehensive discussions of current and potential applications of monoclonal antibody-based agents as frontline and adjuvant treatments in cancer-highlighting the impact of these therapies in areas such as improved response rates and safety profiles while providing an informed understanding of their present limitations. Stimulates exchanges between clinicians and basic scientists working towards the next generation of monoclonal antibody-based agents! Written by a panel of researchers at the cutting edge of therapeutic antibody development, Monoclonal Antibody-Based Therapy of Cancer elucidates the basic, preclinical principles underlying antibody-based therapies examines pivotal results obtained from ongoing clinical trials in malignancies, such as lymphoma and leukemia focuses on a novel monoclonal antibody treatment for non-Hodgkin's lymphoma recently approved by the Food and Drug Administration describes state-of-the-art advances in the management of breast cancer, melanoma, and other solid tumors and more! Together with references to key sources in the literature, tables, drawings, and photographs, this useful resource furnishes excellent direction for medical and radiation oncologists, immunologists, nuclear medicine specialists, hematologists, pharmacologists, biochemists, and graduate and medical school students in these disciplines.

目次

Preclinical Immunotoxin Development, Walter A. Blattler and John M. Lambert Delivery of Monoclonal Antibodies to the Tumor Cell, Rakesh K. Jain Unconjugated Monoclonal Antibody Therapy of Lymphoma, David G. Maloney Clinical Studies with Deglycosylated Ricin A-Chain Immunotoxins, Edward A. Sausville and Ellen S. Vitetta Immunotoxin Therapy of Lymphoma: Studies with Anti-B4-Blocked Ricin, Pratik S. Multani and Michael L. Grossbard Radioimmunoconjugate Therapy of Non-Hodgkin's Lymphoma, Thomas A. Davis and Susan J. Knox Monoclonal Antibody-Based Therapy of Cutaneous T-Cell Non-Hodgkin's Lymphoma, Timothy M. Kuzel and Steven T. Rosen Antibody-Based Therapies for Hodgkin's Disease, H. L. Morein and R. P. Junghans Antibody-Based Therapies for the Treatment of Acute Leukemia, Pratik S. Multani and David J. Flavell Immunotoxin Therapy of Graft-Versus-Host Disease, Carlos R. Bachier and Charles F. LeMaistre Hematopoietic Progenitor-Cell Graft Processing and Treatment, Nadine Beauger and Denis Claude Roy Monoclonal Antibody Therapy for Solid Tumors: An Overview, Panos Fidias Monoclonal Antibody-Based Therapy of Breast Cancer, Francisco J. Esteva and Daniel F. Hayes Monoclonal Antibody-Based Therapy of Melanoma, Marcus O. Butler and Frank G. Haluska Monoclonal Antibodies in the Management of Lung Cancer, Stefan C. Grant, Ellen Early, and John Mendelsohn Monoclonal Antibody-Based Immunoconjugate Therapy of Cancer: Studies with BR96-Doxorubicin, Mansoor N. Saleh, Albert F. LoBuglio, and Pamela A. Trail Immunotoxin Therapy: Past Lessons and Future Directions, Ellen S. Vitetta, Maria-Ana Ghetie, and Victor Ghetie

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