Antiangiogenic agents in cancer therapy
著者
書誌事項
Antiangiogenic agents in cancer therapy
(Cancer drug discovery and development)
Humana Press, c1999
- : alk. paper
大学図書館所蔵 全3件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors summarize our current understanding of tumor growth and its dependence on vascular development, as well as the present status of antiangiogenic agents in preclinical and clinical development. In addition, the book also examines what is known about the mechanisms by which these therapeutic agents interfere with tumor vasculature and grapples with the problem of establishing criteria by which to assess their clinical efficacy. Antiangiogenic Agents in Cancer Therapy offers a unique cutting-edge compendium of antiangiogenic research, taking stock of what has been accomplished , where the experimental therapeutics of antiangiogenic agents is going, and the continuing evolution of their role in cancer treatment and novel drug development.
目次
Part I. Antiangiogenic Factors and Tumor Vasculature. Angiogenesis and Blood Flow in the Solid Tumors, Zishan Haroon, Kevin G. Peters, Charles S. Greenberg, and Mark W. Dewhirst. Oxygenation of Solid Tumors in Animals and Patients, Eric Lartigau and Marcelle Guichard. Role of Inflammatory Mediators in Angiogenesis, Federico Bussolino and Alberto Mantovani. Intra- and Extracellular pH in Solid Tumors, Chang W. Song, HeonJoo Park, and Brian D. Ross. Contribution of the Extracellular Matrix and Macrophages in Angiogenesis, Peter J. Polverini. Regulation of Angiogenesis by the Organ Microenvironment, Diane R. Bielenberg and Isaiah J. Fidler. Fibroblast Growth Factors in Tumor Progression and Angiogenesis, Israel Vlodavsky and Gerhard Christofori. Role of Vascular Endothelial Growth Factor in Regulation of Angiogenesis, Napoleone Ferrara. Regulatory Aspects of Neovascularization: Regulation of Wound Angiogenesis by Metabolic Alterations M. Zamirul Hussain, Q. Perveen Ghani, John J. Feng, and Thomas K. Hunt. Part II. Antiangiogenic Agents. Squalamine: A New Angiostatic Steroid, Jon I. Williams. Cartilage as a Source of Natural Inhibitors of Angiogenesis, Vincent Castronovo, Violetta Dimitriadou, Pierre Savard, Marc Riviere, and Eric Dupont. Thrombospondin as an Inhibitor of Angiogenesis, David W. Dawson and Noel P. Bouk. Matrix Metalloproteinase Inhibitors, Peter D. Brown and Mark Whittaker. Angiostatin and Other Plasminogen Fragments, B. Kim Lee Sim. Dietary and Nutritional Modulation of Tumor Angiogenesis, Purna Mukherjee, Jin-Rong Zhou, Alexander V. Sotnikov, and Steven K. Clinton. Thalidomide and Analogs,Taturo Udagawa, Henk M. W. Verheul, and Robert J. D'Amato. Part III. In Vivo Studies and Clinical Trials. Potentiation of Cytotoxic Cancer Therapies by Antiangiogenic Agents, Beverly A. Teicher. Prognostic Significance of Tumor Vascularity, Gianpietro Gasparini and Adrian L. Harris. Endpoints for Determination of Efficacy of Antiangiogenic Agents in Clinical Trials, William J. Gradishar. Retinoids and Interferons as Antiangiogenic Cancer Drugs, John L. Clifford, Joseph M. Miano, and Scott M. Lippman. Pentosan Polysulfate: A Polysaccharide That Inhibits Angiogenesis by Binding Growth Factors, William D. Figg, James M. Pluda, and Oliver Sartor. TNP-470, Deborah M. Milkowski and Rachelle A. Weiss. Batmastat and Marmastat in Cancer: Summary of Early Clinical Data, Henrik S. Rasmussen. Thalidomide: A Prodrug That Inhibits Angiogenesis, William D. Figg, Eddie Reed, Shawn Green, and James M. Pluda
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