Molecular and applied aspects of oxidative drug metabolizing enzymes
著者
書誌事項
Molecular and applied aspects of oxidative drug metabolizing enzymes
(NATO ASI series, Series A,
Kluwer Acacemic/Plenum Publishers, c1999
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注記
"Published in cooperation with NATO Scientific Affairs Division"
Includes bibliographical references and index
内容説明・目次
内容説明
The NATO Advanced Study Institute of "Molecular and Applied Aspects of Oxida- tive Drug Metabolizing Enzymes" was held in Tekirova, Antalya, Turkey, from August 31 to September 11, 1997. This Institute was the third of a series of the NATO ASIs on a similar topic relating to the enzymes of oxidative metabolism of xenobiotics. The first NATO ASI in this series, entitled "Molecular Aspects of Monooxygenases and Bioactiva- tion of Toxic Compounds" (NATO ASI Series A: Life Sciences, Vol. 202), was held in
目次
- The Fate of Xenobiotics in the Body
- Enzymes of Metabolism
- J.B. Schenkman. Protein-Protein Interactions in the P450 Monooxygenase System
- J.B. Schenkman, et al. Structures of Mitochondrial P450 System Proteins
- I. Hanukoglu. Biochemical Aspects of Flavin-Containing Monooxygenases (FMOs)
- E. Hodgson, et al. Expression and Regulation of Flavin-Containing Monooxygenases
- R.M. Philpot, et al. Correlations between in Vivo and in Vitro Studies in Human Drug Metabolism
- M. Eichelbaum. Pharmacogenetics: Polymorphisms in Xenobiotic Metabolism
- F.J. Gonzalez. Clinical Aspects of Polymorphic Drug Metabolism in Humans
- M. Eichelbaum. Genetic Polymorphisms of Cytochromes P450 1A1 and 2E1 and Glutathione S-Transferase M1 and Cancer Susceptibility in the Human
- M. Watanabe. Cytochrome P450 Isoforms: Insecticide Metabolism in Insects and Mammals and Role in Insecticide Resistance
- E. Hodgson, et al. Inhibitors of CYP51 as Antifungal Agents and Resistance to Azole Antifungals
- S.L. Kelly, et al. The Role of Oxidative Drug Metabolizing Enzymes in Liver and Lung Specific Toxicity
- R.M. Philpot. Importance of Drug Metabolism in Drug Discovery and Development
- R. Gasser. 7 additonal articles. Index.
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