Glycoscience : synthesis of substrate analogs and mimetics

Bibliographic Information

Glycoscience : synthesis of substrate analogs and mimetics

H.Driguez, J.Thiem (eds.)

(Springer desktop editions in chemistry)

New York : Springer-Verlag, 1999

Available at  / 16 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.

Table of Contents

Nucleophilic C-glycosyl donors for C-glycoside synthesis.- Synthesis of C-glycosides of biological interest.- Thiooligosaccharides in glycobiology.- Aldonolactones as chiral synthons.- Chemical and chemo-enzymatic approaches to glycosidase inhibitors with basic nitrogen in the sugar ring.- The synthesis of novel enzyme inhibitors and their use in defining the active sites of glycan hydrolases.- Heparinoid mimetics.- Recent developments in the rational design of multivalent glycoconjugates.- Amphiphilk carbohydrates as a tool for molecular recognition in organized systems.

by "Nielsen BookData"

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Details

  • NCID
    BA42348554
  • ISBN
    • 3540655468
  • Country Code
    gw
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Berlin
  • Pages/Volumes
    312 p.
  • Size
    24 cm
  • Classification
  • Subject Headings
  • Parent Bibliography ID
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