Proceedings of the Thirty-ninth International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues held at Indiana University School of Medicine Indianapolis, Indiana October 5-6, 1998
著者
書誌事項
Proceedings of the Thirty-ninth International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues held at Indiana University School of Medicine Indianapolis, Indiana October 5-6, 1998
（Advances in enzyme regulation, v. 39）
Pergamon Press, c1999
大学図書館所蔵 件 / 全4件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
This volume concentrates on subjects which have reached the stage of productive summarization and critical evaluation in the light of extensive new results. This book also lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies.
目次
- Session I. New Approaches in Anti-cancer Control ( Session Chairman: N.M. Maraldi). Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone
- 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity (Rick A. Finch, Mao-Chin Liu, Ann H. Cory, Joseph G. Cory, A.C. Sartorelli). Causes and consequences of acidic pH in tumors: a magnetic resonance study (M. Stubbs, P.M.J. McSheehy, J.R. Griffiths). Session II. Control of Signal Transduction in Cancer Cells. ( Session Chairman: J.G. Cory). Phosphatidylinositol 3-kinase translocation to the nucleus is an early event in the Interleukin-1 signalling mechanism in human osteosarcoma SAOS-2 cells (N.M. Maraldi, S. Marmiroli, R. Rizzoli, G. Mazzotti, F.A. Manzoli). Amplification of signal transduction capacity and down-regulation by drugs (G. Weber, F. Shen, H. Yang, N. Prajda, W. Li). Session III. Regulation of Homocysteine Metabolism. ( Session Chairman: A.C. Sartorelli). Regulation of homocysteine metabolism (J.D. House, R.L. Jacobs, L.M. Stead, M.E. Brosnan, J.T. Brosnan). Homocysteine metabolism in cardiovascular cells and tissues: implications for hyperhomocysteinemia and cardiovascular disease (P. Chen, R. Poddar, E.V. Tipa, P.M. Dibello, C.D. Moravec, K. Robinson, R. Green, W.D. Kruger, T.A. Garrow, D.W. Jacobsen). Session IV. Mechanisms of Drug Resistance. ( Session Chairman: D. Keppler). Lack of competition of substrates for P-glycoprotein in MCF-7 breast cancer cells overexpressing MDR1 (J.G. Hall, A.H. Cory, J.G. Cory). Genomic amplification of the human DHFR/MSH3 locus remodels mismatch recognition and repair activities (J.T. Drummond). Session V. Regulation of Apoptosis and Metastasis ( Session Chairman: N. Katunuma ). Screening for inducers of apoptosis in apoptosis-resistant human carcinoma cells (K. Umezawa, K. Nakazawa, Y. Uchihata, M. Otsuka). Potassium is a critical regulator of apoptotic enzymes in vitro and in vivo (F.M. Hughes Jr., J.A. Cidlowski). Session VI. Control and Expression of Regulatory Enzymes. ( Session Chairman: O. Greengard). Expression of enzymes of covalent protein modification during regulated and dysregulated proliferation of mammary epithelial cells: PKA, PKC and NMT (R.A. Clegg, P.C. Gordge, W.R. Miller). The regulation of Acetyl-CoA carboxylase-a potential target for the action of hypolipidemic agents (M.R. Munday, C.J. Hemingway). Session VII. New Factor in Resistance. ( Session Chairman: L. Cocco). Export pumps for anionic conjugates encoded by MRP genes (D. Keppler, Y. Cui, J. Konig, I. Leier, A. Nies). Study of the functional share of lysosomal cathepsins by the development of specific inhibitors (N. Katunuma, A. Matsui, T. Kakegawa, , E. Murata, T. Asao, Y. Ohba). Session VIII. Control Mechanisms of Metabolism. ( Session Chairman: M. Stubbs). Folylpoly-Upsilon-glutamate synthetase: generation of isozymes and role in one carbon metabolism and antifolate cytotoxicity (H. Qi, I. Atkins)
「Nielsen BookData」 より