New models for depression
著者
書誌事項
New models for depression
（Advances in biological psychiatry, vol. 19）
Karger, c1998
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
Our scientific approach to depression depends on the theoretical framework available for depression and its etiology, and on the tools we have to investigate brain function. The implication of this means that models of depression will change with time. This book brings together recent updates on the main themes of depression research, presented by active researchers. One major advance has been in brain imaging. Consequently five of the chapters deal with this method, either by examining brain structure, brain function, or functional neurochemistry. A second topic is the renaissance of psychological approaches, both in terms of the neuropsychology of depression and the use of effective psychotherapy as an important adjunct to pharmacology. Recent years have seen a change from one-neurotransmitter explanations to delineating complex relationships and interaction. One such interaction, that between stressm hormones and serotonin, is explored in this volume. Finally, the role of behavioral animal models is discussed. This book will be of immense value to researchers working in the field, as well as clinicians and trainees in understanding the rationale of new diagnostic and treatment approaches. Biologists, pharmacologists and physicians will also benefit from the data on current depression research.
目次
- Cognitive impairment in depression - pyschological models and clinical issues
- neurobehavioural substrates of mood induction
- animal models for depression - the anhedonic rat - theory and practice
- the medial prefrontal cortex in depression
- transcranial magnetic stimulation - a new method for investigating the neuroanatomy of depression
- neurological models of depression
- structural and functional brain markers of age of onset and chronicity in major depressive disorder
- sleep deprivation and dopamine - the psychostimulant theory of antidepressant sleep deprivation
- the pathophysiology of depression - a synthesis of the role of serotonin and corticosteriods.
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