Neurobehavioral genetics : methods and applications

著者

• Jones, Byron C.
• Mormède, Pierre

書誌事項

Neurobehavioral genetics : methods and applications

edited by Byron C. Jones, Pierre Mormède

（CRC Press methods in the life sciences, CRC Press cellular and molecular neuropharmacology）

CRC Press, c1999

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Neurobehavioral Genetics: Methods and Applications covers classic and contemporary approaches to the study of the brain and behavior, including basic and clinical research. This book is designed as a reference for investigators wishing to incorporate genetic methods into neurobehavioral research. A broad spectrum of methods are integrated, unlike any other publication currently in print. Neurobehavioral Genetics: Methods and Applications presents different models, from invertebrates to genetically defined mammals. Introductory chapters demonstrate the scope and power of genetic methods that can be applied to neurobehavioral research from statistical methods and linkage analysis to contemporary molecular genetic approaches to search for candidate genes. The second half of the book covers the applications of quantitative and molecular genetics in basic and clinical research. Topics covered include animal behavior and neurobiology and human clinical problems including neurodegenerative diseases and psychiatric disorders.

目次

A Retrospect on Neurobehavioral Genetics PART 1: BASIC QUANTITATIVE AND STATISTICAL METHODS An Introduction to Quantitative Genetics Planning Genetic Experiments: Power and Sample Size Classical Linkage Analysis PART 2: MOVING FROM MATHEMATICS TO GENES Neurogenetics: Mendelian Genetics - Single-Gene Effects and Some of Their Complicating Factors Quantitative Trait Loci (QTL) Mapping From QTL Detection to Gene Identification-M. P. Moisan Knockouts: Constitutive, Inducible, or Tissue Specific. The Example of 5-HT Receptors-R. Grailhe and R. Hen PART 3: ANIMAL MODELS Behavioral Phenotyping of Transgenic and Knockout Mice-J. N. Crawley Animal Models in Neurobehavioral Genetics: Methods for Estimating Genetic Correlation - John C. Crabbe PART 4: HUMAN METHODS Human Family Studies-L. M. Karkowski The Twin Method-M. Carlier and E. Spitz PART 5: GENE-ENVIRONMENT INTERACTIONS AND MATERNAL EFFECTS Detecting and Measuring Gene-Environment Interaction in Human Temperament (Aggressivity) and Personality Deviation (Conduct Disorder, Antisocial Personality)-K. Riggins-Caspers and R. J. Cadoret Maternal Effects in Behavior Genetic Analysis- M. Carlier, P. Roubertoux, and D. Wahlsten PART 6: METHODS AND APPLICATIONS IN NEUROGENETICS Cerebellar Functions: A Behavioral Neurogenetic Perspective-L. Rondi-Reig, J. Caston, N. Delhaye-Bouchaud, and J. Mariani Natural Genetic Variation of Hippoccampal Structures and Behavior-H. P. Lipp and D. P. Wolfer Human Neurogenetics: Neurodegenerative Diseases-A. D. Durr PART 7: PSYCHIATRIC GENETICS Schizophrenia: Study of a Genetically Complex Phenotype-M. F. Pogue-Geile and I. I. Gottesman Genetics of Autism and Its Place in an Integrated Clinicobiological Approach-S. Tordjman Genetic Basis of Mental Retardation-L. Colleaux PART 8: GENETICS OF AGGRESSION AND EMOTIONALITY Aggression: Concepts and Methods Relevant to Genetic Analyses n Mice and Humans-S. Maxson Genetics and Emotional Behaviors: Experimental Studies-P. Mormede and A. Ramos

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詳細情報

• NII書誌ID(NCID): BA42759730
• ISBN:
  • 0849333644
• LCCN: 99012451
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Boca Raton
• ページ数/冊数: 396 p.
• 大きさ: 25 cm
• 分類:
  • LCC : QP356.22
  • NLM : QH 457
  • DC21 : 612.8
• 件名:
  • LCSH : Neurogenetics -- Research -- Methodology
  • LCSH : Behavior genetics -- Research -- Methodology
  • MESH : Genetics, Behavioral -- methods
• 親書誌ID:
  • BA37063271