Redox regulation of cell signaling and its clinical application

Bibliographic Information

Redox regulation of cell signaling and its clinical application

edited by Lester Packer, Junji Yodoi

(Oxidative stress and disease / series editors, Lester Packer, Enrique Cadenas, 3)

Marcel Dekker, c1999

Available at  / 11 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Presents recent developments in the rapidly expanding field of redox regulation research. The book examines insights into intracellular communication and new techniques for diagnosing and treating diseases associated with oxidation and reduction. It focuses on important cellular mechanisms, such as redox reactions related to thioredoxin (TRX)/adult T-cell leukemia-derived factor (ADF).

Table of Contents

  • Thioredoxin/adult t-cell leukaemia-derived factor (ADF) and redox regulation
  • dysfunction of redox system by reactive oxygen and nitrogen species
  • redox regulation of glucocorticoid hormone action - cross-talk between endocrine stress response and cellular antioxidant system
  • oxidative stress by tumor-derived macrophages induces abnormal structure of t-cell receptor complex
  • structural basis of thioredoxin-mediated redox regulation
  • regulation of yAP-1 nuclear localization in response to oxidative stress
  • a novel antioxidant enzyme, thioredoxin peroxidase and mammalian peroxiredoxins
  • protective action of adult T cell leukaemia derived factor (ADF)/thioredoxin (TRX) against oxidative damage in the kidney of mice treated with a renal carcinogen, ferric nitrilotriacetate - induction and nuclear translocation of ADF/TRX
  • cellular response to lipid peroxidation products
  • primary involvement of oxidative damage and redox imbalance in Alzheimer and other neurodegenerative diseases
  • roles of Syk protein tyrosine kinase in stress-induced signalling in B cells
  • redox regulation of the DNA binding activity in transcription factor PEBP2 - the roles of two conserved cysteine residues
  • reactive oxygen enhanced EGF receptor phosphorylation
  • redox-oriented chemical events in signal transduction in cells
  • mammalian peroxiredoxin MSP23 as an oxidative stress-inducible protein
  • implication of oxidative stress induced in long term uremic complication
  • thioredoxin - a regulatory protein with potential application in medicine and technology
  • the elevated serum level of thioredoxin in patients with chronic and/or malignant liver diseases
  • AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
  • oxygen radicals, redox regulation of the NF-kB signalling and disease control by antioxidants
  • redox regulation of protein function by thioredoxin and glutaredoxin systems
  • therapeutic potential of alpha-lipoic acid - molecular aspects.

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