Chemokines in disease : biology and clinical research
著者
書誌事項
Chemokines in disease : biology and clinical research
(Contemporary immunology, 8)
Humana Press, c1999
大学図書館所蔵 全9件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes index
内容説明・目次
内容説明
Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology. The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory processes. A detailed review of the emerging role of chemokines in viral biology is also presented, with emphasis on HIV biology and novel therapeutic possibilities. Chemokines in Disease: Biology and Clinical Research summarizes the rapidly expanding knowledge of a dazzling array of chemokines and provides fresh insights into the development of powerful new drugs for treating a wide spectrum of diseases.
目次
Part I: Novel Chemokines Discovery and Genetically Engineered Mice. The Chemokine Gene Family: Similar Structures, Diverse Functions, Vicki L. Schweickart, Carol J. Raport, David Chantry, and Patrick W. Gray. Novel Chemokines Identified in Expressed Sequence Tag Databases via Bioinformatics, Kuldeep S. Neote and Shaun R. McColl. Understanding Chemokine Biology Through Mouse Genetics: Riddles and Answers, Craig Gerard. MCP-1 in Human Disease: Insights Gained from Animal Models, Landin Boring, Israel F. Charo, and Barrett J. Rollins. Part II: Chemokines in Inflammatory Disease. IL-8 in Animal Models of Disease, Akihisa Harada and Kouji Matsushima. The Role of Chemokines in the Pathophysiology of the Acute Respiratory Distress Syndrome (ARDS), Thomas R. Martin and Richard B. Goodman. The Role of Chemokines in Allergic Airway Inflammation, Nicholas W. Lukacs. Eotaxin in Disease, Dolores M. Conroy and Timothy J. Williams. The Role of CC Chemokines in Th1- and Th2-Type Pulmonary Inflammation Models, Cory M. Hogaboam, Stephen W. Chensue, and Steven L. Kunkel. Chemokines in Rheumatoid Arthritis, Christine Plater-Zyberk, Jiri Vencovsky, and Christine A. Power. Potential Roles for Chemokines in Transplant Rejection, Ronald P. Gladue and Thomas M. Coffman. Part III: Chemokines in Tumor Biology. The Role of CXC Chemokines in the Regulation of Angiogenesis in Association with Non-Small-Cell Lung Cancer, Robert M. Strieter, Christina L. Addison, Bethany B. Moore, and Douglas A. Arenberg. The Role of ELR+-CXC Chemokines in Wound Healing and Melanoma Biology, Ann Richmond, Jing Luan, Jianguo Du, and Hamid Haghnegahdar. Engineering, Biology, and Clinical Development of hMIP-1a, Lloyd G. Czaplewski, Matthew McCourt, Michael G. Hunter, Brian I. Lord, Andy Millar, and L. Mike Wood. Part IV: Chemokines in Viral Biology. Viral Mimicry of Chemokines and Chemokine Receptors, Sunil K. Ahuja and Philip M. Murphy. The HIV Coreceptor Repertoire: All in the Family of Chemokine Receptors, EdwardA. Berger and Joshua M. Farber. HIV-1 Coreceptors and Viral Tropism, Robert W. Doms and John P. Moore. Mutation Analysis of Receptors and Relationship of Receptor Usage to Disease, Emma J. Aarons and Richard A. Koup. Chemokines and Chemokine Receptors in the Brain: Function in the Normal and Pathophysiologic CNS, Joseph Hesselgesser and Richard Horuk. Antagonism of Chemokine Receptors in Preventing Infection by HIV, Amanda E. I. Proudfoot and Timothy N. C. Wells. Index.
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