Endotoxin in health and disease

著者

    • Brade, Helmut

書誌事項

Endotoxin in health and disease

edited by Helmut Brade ... [et al.]

Marcel Dekker, c1999

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.

目次

  • Endotoxin - historical perspectives
  • lipopolysaccharide and the permeability of the bacterial outer membrane
  • lypopolysacharide phase variation in haemophilus and neisseria
  • antigenic mimicry in neisseris spp
  • antibiotic-induced endotoxin release - important parameters dictating responses
  • complement-mediated lipopolysaccharide release
  • chemical structure of lipid A - recent advances in structural analysis of biologically active molecules
  • chemical structure of the core region of lipopolysaccharides
  • the chemistry of O-polysacharide chains in bacterial lipopolysaccharides
  • the chemistry and biology of lipooligosacharides - the endotoxins of bacteria of the respiratory and genital mucosae
  • a biophysical view on the function and activity of endotoxins
  • lipopolysaccharide preparations in aqueous media -implications for solution versus suspension
  • chlamydia lipopolysaccharides
  • chemical synthesis of lipid A
  • chemical synthesis of core structures
  • microbial pathways of lipid A biosynthesis
  • biosynthesis and genetics of lipopolysaccharides core
  • genetics and biosynthesis of lipopolysacchrides O-antigens
  • lipopolysaccharide-binding protein
  • bactericidal/permeability-increasing protein, P15s and phospholipases A2, endogenous antibiotics in host defense against bacterial infection
  • interactions of lipopolysacharides and lipoproteins
  • effects of human haemoglobin on bacterial endotoxin in vitro and in vivo
  • LPS/lipid A binding synthetic peptides
  • interaction of lipid A and lipopolysaccharide with human serum albumin
  • endothelial cell activation by lipopolysaccharide - role of soluble CD14
  • scavenger receptor and lipopolysaccharide - the role of platelet-activating factor
  • CD14, an innate immune receptor for various bacterial cell wall components
  • the role of MAP kinases, phosphatidylinositol 3-kinase and ceramide in LPS-induced signalling in macrophages
  • endotoxin effects on synthesis of phosphatidic acid and phosphatidic acid-derived diacylglyceride species. (Part contents).

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詳細情報

  • NII書誌ID(NCID)
    BA43691428
  • ISBN
    • 0824719441
  • LCCN
    99029165
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    New York
  • ページ数/冊数
    xviii, 950 p.
  • 大きさ
    29 cm
  • 分類
  • 件名
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