Varicella-Zoster virus : molecular biology, pathogenesis, and clinical aspects

書誌事項

Varicella-Zoster virus : molecular biology, pathogenesis, and clinical aspects

volume editors, Manfred H. Wolff, Stefan Schunemann, Axel Schmidt

(Contributions to microbiology, vol. 3)

Karger, 1999

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注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

Varicella-zoster virus (VZV), a member of the herpesvirus family, is known as the causative agent of chickenpox (varicella) and shingles (zoster). In the past decades, considerable knowledge about the transmission as well as the clinical and epidemiological aspects of VZV infection has been accumulated. Nowadays effective treatment is available and a vaccine has been developed and licensed. This book provides a comprehensive overview of our current knowledge of the molecular biology and the clinical aspects of VZV. Written by international experts in the field, individual chapters cover the diagnosis, pathogenesis, therapy and epidemiology of VZV infection. In addition, recent research findings concerning the viral genome structure, the replication cycle, the mechanisms of latency and reactivation, as well as the development of new vaccines are described. Authoritative and up to date, this volume is a vital reference not only for researchers in the herpesvirus field, but also for clinical microbiologists, dermatologists, pediatricians, and physicians in general and internal medicine.

目次

  • General aspects: morphological and biological characteristics of varicella-zoster virus, M. Rahaus et al
  • genomic structure and organization of varicella-zoster virus, J.I. Cohen
  • overview of the replication cycle of varicella-zoster virus, C. Sadzot-Delvaux et al
  • role of glycoproteins in varicella-zoster virus infection, M.D. Gershon and A.A. Gershon
  • varicella-zoster virus - latency and reactivation, O. Lungu and P.W. Annunziato. Pathogenesis and clinical aspects: epidemiology of varicella infections, A. Flisser and R. Tapia-Conyer
  • viremic stages of different varicella-zoster associated diseases, S. Schunemann et al
  • chickenpox (varicella), A.M. Arvin
  • shingles (zoster), H.M. Lilie and S.W. Wassilew
  • postherpatic neuralgia, C.P.N. Watson
  • infections during pregnancy, P. Wutzler and A. Sauerbrei
  • diagnosis of varicella-zoster virus-associated diseases with special emphasis on infections in the immunocompromised host, M.H. Wolff et al
  • approaches to the treatment of varicella-zoster virus infections, R.J. Whitley
  • experience with live-attenuated varicella-zoster vaccines, P. LaRussa
  • development of recombitant varicella-zoster virus vaccines, A.M. Arvin et al.

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