Immune response and the eye
著者
書誌事項
Immune response and the eye
(Chemical immunology, v. 73)
Karger, c1999
大学図書館所蔵 全7件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
The primary purpose of this volume on immune responses and the eye is to describe, explain and speculate on what is known and understood about the consequences of the eye-immune system compromise, from the eye's standpoint. The research of the last two decades of the 20th century has witnessed remarkable advances in knowledge of the physiology of ocular immune privilege. The chapters in this book address this body of knowledge, looking at information gained concerning the mechanisms responsible for ocular inflammation secondary to viral, autoimmune and other immunopathogenic processes. Also, an understanding of immune responses in normal and inflamed eyes is used to explain the immunologic processes involved in the growth of ocular tumours and in the success and failure of transplants of cornea and retina.
目次
- Part 1 Introduction - all for saving the visual axis: the unusual nature of ocular immunity and inflammation
- immune mechanisms where the blood-ocular barrier meets the general circulation
- corneal endotheliitis and its related disorders
- teas as "Trojan horses" bearing ocular pathogens
- allergic conjunctival disorders
- the battle against cicatrizing ocular surface disorders
- molecular mimicry and autoimmune diseases of the eye
- antigen/pathogen clearance and connective tissue destruction
- concluding remarks. Part 2 Regional immunity and ocular immune privilege: principles of immune responses
- the immune reflex arc
- immune regulation, tolerance and the immune reflex arc
- concept of regional immunity
- understanding the mechanisms of immune privilege - influence of immune privilege on the immune reflex arc
- rationale for immune privilege in the eye. Part 3 Molecular and cellular aspects of allergic conjunctivits: animal models
- clinical studies
- mechanism of the allergic reaction
- timecourse of response
- T-cell-derived mediators and cytokines
- mast cells and mast cell mediators
- treatment of allergic conjunctivitis
- concluding remarks. Part 4 Anterior chamber-associated immune deviation: characteristics of ACAID
- is ACAID a Th2 immune response?
- role of antigen in the induction of ACAID
- role of the camerosplenic axis in ACAID
- role of fasL-induced apoptosis in ACAID
- diverging hyptheses on the induction and expression of ACAID
- what is the significance of ACAID?. Part 5 Ocular immunosuppressive microenvironment: introduction
- aqueous humour factors that suppress DTH
- immune responses modified by normal aqueous humour. Part 6 Mechanisms of intraocular inflammation: introduction
- nonspecific immune response
- antigen-specific immune response. Part 7 Immunopathogenesis of viral ocular infections: introduction
- viral infections involving the eye
- herpes simplex virus (HSV) ocular disease
- herpes simplex keratitis
- immunopathological mechanisms of HSK as defined in the mouse model
- antigen presentation in the HSV-1-infected cornea
- does HSV-1 trigger an autoimmune response in the cornea?. Part 8 Immune privilege, tumours and the eye: tumours as immune privileged sites and privileged tissues
- tumour antigens
- tumour escape mechanisms
- tumour escape following active immunization of cancer patients
- comparing immune privilege within the eye and tumours. Part 9 Immunopathogenic mechanisms in intraocular inflammation: introduction - what is uveitis?
- causes of IOI
- pathology of IOI
- how is IOI induced?
- experimental models
- evidence for systemic activation of T cells in uveitis
- mechanisms of tissue damage in IOI
- regulatory mechanisms in the eye and how these are disabled in IOI. Part 10 Immunobiology and immunopathology of corneal transplantation. Part 11 Retinal transplantation.
「Nielsen BookData」 より