Transport and trafficking in the malaria-infected erythrocyte

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書誌事項

Transport and trafficking in the malaria-infected erythrocyte

[editors, Gregory R. Bock and Gail Cardew]

(Novartis Foundation symposium, 226)

John Wiley, 1999

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Malaria is still one of the world's major infectious diseases. It presently affects 500 million people, and causes the death of 1.5-2.5 million people annually. The emergence of drug resistance in the parasite calls for the development of new drugs, and knowledge of specific biochemical processes in the malaria-infected erythrocyte could provide a basis for this development. This book discusses the transport of solutes into and out of the infected cell, the use of specific transport modalities for the specific targeting of drugs, and the traffic of proteins produced by the parasite in the infected cells, as an essential process for the biogenesis of transport systems.

目次

  • Red blood cell membrane transport
  • chemical and physical in vitro alterations of the erythrocyte membrane: a model for its pathophysiological states?
  • the effects of transport perturbations on the homeostasis of red blood cells
  • transport properties of the host cell membrane
  • a nutrient-permeable channel on the intraerythrocytic malaria parasite
  • the permeability properties of the parasite cell membrane
  • the ins and outs of macromolecular transport in malaria-infected erythrocytes
  • expression of parasite transporters in xenopus oocytes
  • trafficking by malaria parasites: a model for vacuolar targets. (part contents)

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