Intracellular bacterial vaccine vectors : immunology, cell biology, and genetics

著者

書誌事項

Intracellular bacterial vaccine vectors : immunology, cell biology, and genetics

edited by Yvonne Paterson

Wiley-Liss, c1999

大学図書館所蔵 件 / 全6件

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注記

Includes index

内容説明・目次

内容説明

Host defense against infectious microorganisms is becoming an intensively studied topic; recent advances in immunology and microbiology have resulted in a substantially improved understanding of the pathways used by a variety of microorganisms to infect humans. This resource provides up-to-date reviews of the invasion strategies utilized by selected bacteria and then shows how these microorganisms can be manipulated to generate potential vaccines. The book begins with a comprehensive review of the relationship between bacterial life-styles and immune responsiveness to bacterial antigens. The book is divided into two parts: Part 1 describes basic research intended primarily for academic scientists. Included in this section are chapters describing the use of Listeria monocytogenes, Salmonella typhimurium and Bacillus Calmette-Guerin (BCG) to invoke different types of immune response. Part 2 describes the application of the engineered Listeria monocytogenes as a vaccine against specific tumors and the use of recombinant Salmonella and BCG in clinical trials for HIV and TB

目次

  • The Relationship between Intra--Cellular Bacterial Life--Styles and the Immune Responsiveness to Bacterial Delivered Antigens (Y. Paterson).
  • THE BIOLOGY AND IMMUNOLOGY OF INTRACELLULAR BACTERIAL VECTORS.
  • The Immune Response to Mycobacteria (D. Young & J. Thole).
  • Mucosal Immune Defense: The Salmonella typhimurium MODEL (T. Eisenstein).
  • Cell Biology and Immune Response to Listeria monocytogenes, AN INTRACELLULAR PATHOGEN (S. Vijh & E. Pamer).
  • VACCINE STRATEGIES USING LIVE RECOMBINANT INTRACELLULAR BACTERIA.
  • Recombinant BCG Vaccines (A. Aldovini & R. Young).
  • Mucosal Vaccination with Salmonella Vaccine Vectors (D. Hone, et al.).
  • The Use of Listeria monocytogenes Recombinants as Vaccine Vectors in Infectious and Neoplastic Disease (L. Weiskirch & Y. Paterson).
  • Index.

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