Primer on the metabolic bone diseases and disorders of mineral metabolism

書誌事項

Primer on the metabolic bone diseases and disorders of mineral metabolism

editor, Murray J. Favus ; associate editors, Sylvia Christakos ... [et al.]

Lippincott Williams & Wilkins, c1999

4th ed

大学図書館所蔵 件 / 9

この図書・雑誌をさがす

注記

"An official publication of the American Society for Bone and Mineral Research"--P. preceding t.p

Includes bibliographical references and index

内容説明・目次

内容説明

For clinicians who see patients with disorders of mineral metabolism, metabolic bone diseases, or disorders of stone formation, this text provides information on the symptoms, pathophysiology, diagnosis and treatment of all common and rare bone and mineral disorders. Two sections new to this edition cover skeletal physiology throughout the life cycle and dental problems. Other chapters cover pharmacology of osteoporosis treatment and osteoporosis and organ transplantation.

目次

  • Part 1 Anatomy and biology of bone matrix and cellular elements: anatomy and ultrastructure of bone
  • bone morphogenesis and embryologic development
  • bone formation - osteoblast lineage cells, growth factors, matrix proteins and the mineralization process
  • bone remodelling
  • biomechanics of bone. Part 2 Skeletal physiology: childhood and adolescence
  • pregnancy and lactation
  • menopause
  • the aging skeleton. Part 3 Mineral homeostasis: the intestinal absorption of calcium, magnesium and phosphate
  • calcium, magnesium and phosphorus - renal handling and urinary excretion
  • mineral balance and homeostasis
  • parathyroid hormone
  • parathyroid hormone-related protein
  • vitamin D - photobiology, metabolism, mechanism of action and clinical applications
  • calcitonin
  • gonadal steroids and receptors. Part 4 Clinical evaluation of bone and mineral disorders: history and physical examination
  • blood calcium, phosphorus and magnesium
  • assay methods - parathyroid hormone, parathyroid hormone-related protein and calcitonin
  • vitamin D metabolites
  • biochemical markers of bone turnover
  • radiologic evaluation of bone mineral in children
  • scintigraphy in metabolic bone disease
  • clinical application of bone densitometry
  • radiology of osteoporosis
  • bone biopsy and histomorphometry in clinical practice
  • molecular diagnosis of bone and mineral disorders. Part 5 Disorders of serum minerals: hypercalcaemia - pathogenesis, clinical manifestations, differential diagnosis and management
  • primary hyperparathyroidism
  • familial hyperparathyroid syndromes
  • familial hypocalciuric hypercalcaemia
  • tertiary hyperparathyroidism and refractory secondary hyperparathyroidism
  • humoral hypercalcaemia of malignancy
  • hypercalcaemia in haematologic malignancies and in solid tumors associated with extensive localized bone destruction
  • hypercalcaemia due to granuloma-forming disorders
  • miscellaneous causes of hypercalcaemia
  • hypercalcaemic syndromes in infants and children
  • hypocalcaemia - pathogenesis, differential diagnosis and management
  • hypoparathyroidism
  • parathyroid hormone resistance syndromes
  • neonatal hypocalcaemia
  • miscellaneous causes of hypocalcaemia
  • magnesium depletion and hypermagnesemia
  • hyperphosphatemia and hypophosphatemia. Part 6 Metabolic bone diseases: epidemiology of osteoporosis
  • pathogenesis of postmenopausal osteoporosis
  • physical activity and regulation of bone mass
  • prevention of osteoporosis
  • nutrition and osteoporosis
  • evaluation of postmenopausal osteoporosis
  • pharmacology of agents to treat osteoporosis
  • pharmacologic treatment of postmenopausal osteoporosis
  • osteoporosis in men
  • glucocorticoid-induced osteoporosis
  • transplantation osteoporosis
  • juvenile osteoporosis
  • secondary causes of osteoporosis - thyrotoxicosis and lack of weight bearing
  • orthopaedic complications of osteoporosis
  • osteoporosis and rheumatic diseases
  • nutritional rickets and osteomalacia
  • metabolic bone disease of total parental nutrition
  • vitamin D-dependent rickets
  • hypophosphatemic vitamin D-resi

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