Adaptive evolution of genes and genomes


    • Hughes, Austin L.


Adaptive evolution of genes and genomes

Austin L. Hughes

Oxford University Press, 1999

大学図書館所蔵 件 / 17



Includes bibliographical references (p. 241-263) and index



This valuable book thoroughly examines adaptive evolution at the DNA level while taking a comprehensive look at the research being done in the area. It presents useful cases where signals of adaptive evolution are detected through neutral molecular evolution, providing a powerful strategy for testing the Darwinian hypothesis of natural selection. By bridging the gap between research on molecular and phenotype evolution and contributing to the unification of the biological sciences, this book will especially appeal to researchers and graduate students in the field of evolutionary biology. Also, with its focus on particular protein molecules and on specific domains of these proteins, it will benefit a wider audience of both evolutionary and functional biologists.


  • What is adaptive evolution?
  • methods of sequence analysis
  • the neutral theory
  • balancing selection: the major histocompatibility complex
  • balancing selection - other examples
  • directional selection
  • evolution of new protein function
  • adaptive characteristics of genomes.

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