Statins : the HMG CoA reductase inhibitors in perspective
著者
書誌事項
Statins : the HMG CoA reductase inhibitors in perspective
Martin Dunitz, c2000
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内容説明・目次
内容説明
A comprehensive compendium of the clinical trial data available, with each statin's different qualities explained, this text is intended as a guide to hypercholesterolaemia for both experienced clinicians and trainees.
目次
1. Hyperlipidaemia as a Risk Factor for Vascular Disease 2. Lipid Control in the Pre-Statin Era 3. Discovery and Development of the Statins 4. Comparative Chemistry, Pharmacology and Mechanism of Action of the Statins 5. Ancillary Benefits of the Statins 6. Progression and Regression of Coronary Atherosclerosis Observational Studies and (Statin) Interventional Trials in Perspective 7. The Scandanavian Simvastatin Study (4S) 8. Primary Prevention of Coronary Heart Disease with Statins 9. The CARE (Cholesterol and Recurrent Events) Trial: The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels 10. Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) Study: Results and Implications for Clinical Practice 11. Statin Therapy Following Vascular Surgery 12. Guidelines for Clinical Use of the Statins 13. Cost-effectiveness of Statin Use 14. Current and Future Clinical Trials 15. Statin Therapy for a New Millenium
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