Human gene evolution
著者
書誌事項
Human gene evolution
（The Human molecular genetics series / series advisors, D.N. Cooper, S.E. Humphries, T. Strachan）
Bios, 1999
- : us
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注記
Includes bibliographical references and indexes
内容説明・目次
- 巻冊次
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: us ISBN 9780121878702
内容説明
Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field.
目次
Preface.
Abbreviations.
Introduction and Overview:
Structure and Function in the Human Genome.
Evolution of the Human Genome.
Evolution of Gene Structure:
Introns, Exons and Evolution.
Genes and Gene Families.
Promoters and Transcription Factors.
Pseudogenes and their Formation.
Mutational Mechanisms in Evolution:
Single Base-pair Substitutions.
Contractions and Expansions in Gene Size and Number.
Gross Gene Rearrangements.
Molecular Reconstruction of Ancient Genes/Proteins.
Indices of Human Gene Symbols used in the text.
Index.
- 巻冊次
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ISBN 9781859961513
内容説明
The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.
目次
Part 1. Introduction and Overview. 1. Structure and Function in the Human Genomes. 2. Evolution of the Human Genomes. Part 2. Evolution of Gene Structure. 3. Introns, Exons and Evolution. 4. Genes and Gene Families. 5. Promoters and Transcriptions Factors. 6. Pseudigenes and their Formation. Part 3. Mutational Mechanisms in Evolution. 7. Single Base-pair Substitutions. 8. Contractions and Expansions in Gene Size and Number. 9. Genes and Rearrangements. 10. Molecular Reconstruction of Ancient Genes/Proteins.
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