The foundations of structural biology
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書誌事項
The foundations of structural biology
Academic Press, c2000
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内容説明・目次
内容説明
Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules.
目次
Introduction to Protein Structure.Solid State and Solution Methods for Determining Biological Macromolecular Structure.Crystallographic Coordinates and Stereodrawings.Properties of Biomacromolecules in the Crystalline State.Quaternary Structure of Proteins.Secondary Structure of Proteins.Domains and Super-secondary Structure.Conformational States in Crystal and NMR Structures.Hydrogen Bonds and Water Molecules in Crystalline Proteins.Protein and Nucleic Acid Complexes.Metal Ions Bound to Proteins.Lipid Protein Interactions.
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