Bioinformatics methods and protocols
著者
書誌事項
Bioinformatics methods and protocols
(Methods in molecular biology / John M. Walker, series editor, v. 132)
Humana Press, c2000
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Computers have become an essential component of modern biology. They help to manage the vast and increasing amount of biological data and continue to play an integral role in the discovery of new biological relationships. This in silico approach to biology has helped to reshape the modern biological sciences. With the biological revolution now among us, it is imperative that each scientist develop and hone today's bioinformatics skills, if only at a rudimentary level. Bioinformatics Methods and Protocols was conceived as part of the Methods in Molecular Biology series to meet this challenge and to provide the experienced user with useful tips and an up-to-date overview of current developments. It builds upon the foundation that was provided in the two-volume set published in 1994 entitled Computer Analysis of Sequence Data. We divided Bioinformatics Methods and Protocols into five parts, including a thorough survey of the basic sequence analysis software packages that are available at most institutions, as well as the design and implemen- tion of an essential introductory Bioinformatics course. In addition, we included sections describing specialized noncommercial software, databases, and other resources available as part of the World Wide Web and a stimul- ing discussion of some of the computational challenges biologists now face and likely future solutions.
目次
Part 1. Sequence Analysis Packages
GCG: The Wisconsin Package of Sequence Analysis Programs
David D. Womble
Web-Based Interfaces for the GCG Sequence Analysis Programs
David D. Womble
Omiga: A PC-Based Sequence Analysis Tool
Jeffrey A. Kramer
MacVector: Integrated Sequence Analysis for the Macintosh
Promila A. Rastogi
DNASTAR's Lasergene Sequence Analysis Software
Timothy G. Burland
PepTool (TM) and GeneTool (TM): Platform-Independent Tools for Biological Sequence Analysis
David S. Wishart, Paul Stothard, and Gary H. Van Domselaar
The Staden Package, 1998
Rodger Staden, Kathryn F. Beal, and James K. Bonfield
Building a Multiuser Sequence Analysis Facility Using Freeware
Brian Fristensky
Part 2. Molecular Biology Software
Free Software in Molecular Biology for Macintosh and MS Windows Computers
Appendix: Software Listings
Don Gilbert
Flexible Sequence Similarity Searching with the FASTA3 Program Package
William R. Pearson
The Use of CLUSTAL W and CLUSTAL X for Multiple Sequence Alignment
Ashok Aiyar
Phylogenetic Analysis Using PHYLIP
Jacques D. Retief
Annotating Sequence Data Using Genotator
Nomi L. Harris
Low Cost Gel Analysis
Jeffry A. Reidler
Part 3. Web-Based Resources
Computer Resources for the Clinical and Molecular Geneticist
Yuval Yaron and Avi Orr-Urtreger
The NCBI: Publicly Available Tools and Resources on the Web
Jack P. Jenuth
Resources at EBI
Patricia Rodriguez-Tome
Computer-Assisted Analysis of Transcription Control Regions: MatInspector and Other Programs
Thomas Werner
Computational Approaches for Gene Identification
Gautam B. Singh
Primer3 on the WWW for General Users and for Biologist Programmers
Steve Rozen andHelen Skaletsky
Using the WWW to Supply the Molecular Biology Lab
MaryAnn Labant and Roger Anderson
Part 4. Computers and Molecular Biology: Issues and Constraints
Network Computing: Restructuring How Scientists Use Computers and What We Get Out of Them
Brian Fristensky
Computing with DNA
Lila Kari and Laura F. Landweber
Detecting Biological Patterns: The Integration of Databases, Models, and Algorithms
Gautam B. Singh
Part 5. Teaching Bioinformatics and Keeping Up-to-Date with the Literature
Design and Implementation of an Introductory Course for Computer Applications in Molecular Biology and Genetics
Stephen A. Krawetz
The Virtual Library I: Searching MEDLINE
Keir Reavie
The Virtual Library II: Science Citation Index and Current Awareness Services
Keir Reavie
The Virtual Library III: Electronic Journals, Grants, and Funding Information
Keir Reavie
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