Handbook of chiral chemicals

書誌事項

Handbook of chiral chemicals

edited by David J. Ager

M. Dekker, c1999

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Describes the problems associated with large, commercial-scale syntheses of chiral molecules and the relatively small number of reactions that can be used to achieve these syntheses. The book discusses commercially viable and still-developing methods of compound manufacture, and reviews the best-selling chiral compounds as of 1996.

目次

  • Sourcing chiral compounds for the pharmaceutical industry
  • synthesis of large volume products
  • synthesis of phenylalanine by fermentation and chemo-enzymatic methods
  • carbohydrates
  • terpenes - the expansion of the chiral pool
  • substitution reactions
  • resolutions at large scale - case studies
  • transition metal catalyzed hydrogenations, isomerizations, and other reactions
  • pericyclic reactions
  • asymmetric reduction of prochiral ketones catalyzed by oxazaborolidines
  • asymmetric of

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