CiNii Books - A textbook of clinical pharmacology

Clinical pharmacology remains at the heart of surgical and medical practice, and this comprehensive textbook introduces the major topics. It describes in detail the therapeutic use of the ever increasing catalogue of medical drugs available for prescription by a physician/nurse practitioner. All areas of drug prescribing are covered and have been updated since the previous edition, especially the rapidly changing fields of HIV treatment and biotechnology drugs. 'The Textbook of Clinical Pharmacology', 4th edition adopts a systems-based approach and covers the core syllabus for medical undergraduates. In this edition, new chapters on drugs and the eye, and molecular therapeutics have been included. Key points have been highlighted for revision and challenging clinical pharmacology cases will help the reader to assess their learning. The improvements to this edition of a 'Textbook of Clinical Pharmacology' ensures that the book remains the core text for undergraduates.

Table of Contents

Part 1 General Principles Introduction to therapeutics Mechanisms of drug action (pharmaco-dynamics) Pharmacokinetics Drug absorption and routes of administration Drug metabolism Renal excretion of drugs Effects of disease on drug disposition Therapeutic drug monitoring Drugs in pregnancy Drugs in infants and children Drugs in the elderly Adverse drug reactions Drug interactions Pharmacogenetics Introduction of new drugs and clinical trials Biotechnology and gene therapy Part 2 The Nervous System Hypnotics and anxiolytics Schizophrenia and behavioural emergencies Mood disorders Movement disorders and degenerative CNS disease Anticonvulsants Migraine Anaesthetics and muscle relaxants Analgesics and the control of pain Part 3 The Musculoskeletal System Anti-inflammatory drugs and the treatment of arthritis Part 4 The Cardiovascular System Prevention of Atheroma: lowering plasma cholesterol and other approaches Hypertension Ischaemic heart disease Anticoagulants and antiplatelet drugs Heart failure Cardiac arrhythmias Part 5 The Respiratory System Therapy of asthma, COAD and other respiratory disorders Part 6 The Alimentary System Alimentary system and liver Vitamins and other nutrients Part 7 Fluids and Electrolytes Drugs and the renal and genitourinary systems: fluid and electrolyte disorders Part 8 The Endocrine System Diabetes mellitus Thyroid Calcium metabolism Adrenal hormones Reproductive endocrinology Pituitary Part 9 Selective Toxicity Antibacterial drugs Mycobacterial infections Fungal and viral infections HIV and AIDS Malaria and other parasitic infections Cancer chemotherapy Part 10 Haematology Anaemia and other haematological disorders Part 11 Immunopharmacology Clinical immunopharmacology Part 12 The Skin Drugs and the skin Part 13 The Eye Drugs and the eye Part 14 Clinical Toxicology Drug and alcohol abuse Drug overdose and poisoning Appendix.

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A textbook of clinical pharmacology

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