Organic synthesis on solid phase : supports, linkers, reactions
Author(s)
Bibliographic Information
Organic synthesis on solid phase : supports, linkers, reactions
Wiley-VCH, c2000
Available at / 12 libraries
-
No Libraries matched.
- Remove all filters.
Note
Includes bibliographical references & index
Description and Table of Contents
Description
Organic synthesis on solid supports is a rapidly developing methodology, which offers several advantages if compared to traditional synthesis in solution. In recent years the number of substance classes that can be synthesized on solid phase has quickly increased, and solid-phase synthesis is becoming a valuable alternative to traditional synthesis - in particular when large numbers of different compounds in small quantities are needed for screening. This exhaustive and systematically organized reference work gives an in-depth view on organic syntheses on insoluble polymers from the basic principles to the newest developments. The work quickly guides the reader to any particular type of reaction and to the best method for preparing a given class of compounds on solid support. Many tables with clear presentation collect valuable information about the feasibility of a given reaction on solid support, and a wealth of information is opened up to the reader through a thoroughly worked out and comprehensive reference list.
Table of Contents
- Part 1 Bond formation on solid phase: resins and linkers: resins/ supports (e.g. polystyrene, tentagel, silicates, cellulose)/ linkers (arranged according to cleavage methods)
- attachment of organic compounds to solid supports (table indicating which type of compound can be attached to a support with a given linker, and in which section of the book this subject is treated)
- acylation reactions: C-/N-/O-/S- and other acylations
- alkylation reactions: C-/N-/O-/S- and other acylations
- arylation reactions: C-/N-/O-/S- and other acylations
- olefination reactions
- cycloaddition reactions
- miscellaneous. Part 2: Functional-group transformation on solid phase
- synthesis of individual classes of compounds: functional-group transformations on solid phase: reductions - oxidations - rearrangements - eliminations and fragmentations - protective groups on solid phase synthesis
- synthesis of individual classes of compounds: solid phase synthesis of heterocycles - solid phase synthesis of oligomeric compounds - solid phase synthesis of natural products.
by "Nielsen BookData"
