Amino acid derivatives : a practical approach
著者
書誌事項
Amino acid derivatives : a practical approach
(The practical approach in chemistry series)
Oxford University Press, c1999
- : hbk
大学図書館所蔵 全13件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Many successful syntheses of homochiral organic compounds use an amino acid derivative as a starting point. Such syntheses are not confined to peptides as targets; peptide synthesis strategies have been narrowed down to a few well-defined protocols (and these are not covered in this book). Outside the peptide field, many non-routine syntheses have been established that give the intended products in which the structural features of the starting amino acid are barely
recognisable. This book is a laboratory guide that covers the early stages of syntheses under these headings, which invariably call for modifications to the functional groups of readily-available L-amino acids. It will therefore give invaluable guidance to the preparation of amino acid derivatives
to be used not only in these broad area of synthesis but also in amino acid analysis. Synthetic work with amino acids carried out by new users and by experienced chemists and other scientists, will be supported by the detailed practical protocols and background information provided in this book.
目次
- Preface
- 1. Introduction
- 2. Acylation and alkoxycarbonylation of the amino group
- 3. Thioacylatin of the amino group of amino acids
- 4. Mono- and Di-alkylatin of the amino group
- 5. Reactions at the carboxy group of an amino acid: Amino acid salts
- 6. Reactions at the carboxy group of an amino acid: Esterification of amino acids
- 7. Carboxy group modifications
- synthesis of a homochiral ketone derived from L-tryptophan
- 8. Synthons derived from Aspartic and glutamic acids
- 9. Benzophenone schiff bases of a-Amino acid esters as electrophiles. Addition of grignard reagents and alkly-lithiums to produce threo-amino alcohols and aminopolyols
- 10. Synthetic uses of serine, threonine and cysteine
- 11. Synthetic uses of methionine
- 12. Metal-mediated modification of the side-chains of a-amino acids
- 13. Diastereocontrolled functionalisation of enantiomerically pure 5-phenyl-1, 4-Oxazin-2-ones by azomethine ylid generation and trapping
- 14. Reductive modifications of the carboxy-group
- 15. Reactions at the a-Carbon Atom of a-Amino acid derivatives
- 16. Modifications of the Aryl substitutents of a- and beta-aryl a-amino acids
- 17. Isolation and chromatographic purification of reaction products from amino acids
- Index
「Nielsen BookData」 より