Neuroendocrinology of leptin

著者

書誌事項

Neuroendocrinology of leptin

volume editor, Ehud Ur

（Frontiers of hormone research, v. 26）

Karger, 1999

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The discovery of the adipostatic hormone leptin has transformed our understanding of the neurobiology of appetite control and has helped to establish the biological basis of obesity. In recent years there has been a wealth of publications relating to the physiology of this peptide. This volume sets out to draw together key features of the central effects of leptin. Contributions from leading authorities in the field include reviews of leptin's actions on hypothalamic peptides, the role of leptin in fasting, its effects on reproductive function, and evidence supporting endogenous brain production of the peptide. Endocrinologists, diabetologists, obesity specialists and Neurobiologists will be interested in this succint and timely review of the effects of the adipostatic hormone leptin on neuroendocrine function.

目次

  • Introduction, E. Ur
  • neurobiology of OB protein (leptin), L.A. Campfield
  • central mechanisms responsible for the actions of OB protein (leptin) on food intake, metabolism and body energy storage, L.A. Campfield
  • anatomic basis of leptin action in the hypothalamus, J.K. Elmquist
  • leptin and the neuroendocrinology of fasting, R.S. Ahima
  • leptin regulation of proopiomelanocortin, Ch. Mobbs and T. Mizuno
  • hypothalamic neuropeptide Y and its neuroendocrine regulation by leptin, P.S. Widdowson and J.P.H. Wilding
  • perspectives on leptin's role as a metabolic signal for the onset of puberty, C.C. Cheung et al
  • the brain is a source of leptin, M. Wilkinson et al.

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