Clinical research in diabetes and obesity
著者
書誌事項
Clinical research in diabetes and obesity
（Contemporary biomedicine）
Humana Press, c1997
- v. 1 : alk. paper
- v. 2 : alk. paper
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注記
Includes bibliographical references and indexes
収録内容
- v.1. Methods, assessment, and metabolic regulation
- v. 2. Diabetes and obesity
内容説明・目次
- 巻冊次
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v. 1 : alk. paper ISBN 9780896033504
内容説明
An unprecedented compilation of state-of-the-art advances in clinical research on diabetes and obesity by premier clinical scientists around the world. This volume critically reviews the limitations and strengths of today's major techniques in clinical diabetes research, and then reviews how those methods have been used to carry out cutting-edge studies of carbohydrate, lipid, and protein metabolism in the disease.
目次
Part I: Methods in Clinical Research. Assessment of B-Cell Function in Humans: Approach and Interpretation, Steven E. Kahn. In Vivo Measurement of Insulin Sensitivity in Humans, Masafumi Matsuda and Ralph A. DeFronzo. Insulin Action in Skeletal Muscle: In Vivo Assessment, Lawrence J. Mandarino. Glucose Effectiveness, Richard N. Bergman, Ta-Chen Ni, and Marilyn Ader. Assessment of Substrate and Energy Metabolism in Vivo, Keith N. Frayn and Ian A. Macdonald. Assessment of Free Fatty Acid Metabolism, Michael D. Jensen. Assessment of Protein Metabolism in Diabetes, K. Sreekumaran Nair. Assessment Methods of Carbohydrate Metabolism in the Liver (Glycogenolysis, Gluconeogenesis, and Glycogen Synthesis), Jerry Radziuk. Part II: Effect of Hormones on Substrate Metabolism. Insulin Effects on Substrate Metabolism, William G. Blankard and John N. Clore. The Metabolic Actions of Glucagon, Alan D. Cherrington. The Effects of Glucocorticoid Hormones on Substrate Metabolism, Sean F. Dinneen. The Role of Growth Hormone, Niels Moller, Hans Orskov, and Ole Schmitz. Interrelationships Between the Central Nervous System and Peripheral Glucose Metabolism, Patrick J. Boyle. Part III: Regulation of Metabolism in Humans: Postabsorptive and Postprandial States. Regulation of Carbohydrate Metabolism, Roy Taylor and Gerald I. Shulman. Effects of Lipids on Blood Glucose Regulation and Insulin Action, Edward W. Kraegen, David G. P. Carey, and Lesley V. Campbell. Protein Metabolism in Healthy and Diabetic Humans, Eugene J. Barrett and David A. Fryburg. Regulation of Fuel Metabolism During Exercise, Amy E. Halseth, Pietro Galassetti, and David H. Wasserman. Glucose Counterregulation, John E. Gerich. Index.
- 巻冊次
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v. 2 : alk. paper ISBN 9780896034921
内容説明
An unprecedented compilation of state-of-the-art advances in clinical research by premier clinical scientists around the world. This volume discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus. Along the way, the authoritative contributors writing here illuminate how changes in the hormone action and substrate metabolism of healthy humans may lead to obesity and noninsulin-dependent diabetes mellitus.
目次
Part I: Obesity. Energy Metabolism and Obesity, James O. Hill. Metabolic Parameters and Energy Expenditure Before and After Weight Loss, John M. Amatruda. Regulation of Food Intake and Body Weight, Michael W. Schwartz, Denis G. Baskin, Karl J. Kaiyala, Steven C. Woods, and Daniel Porte, Jr. Mechanisms of Insulin Resistance in Obesity, David E. Kelley and Jean-Aime Simoneau. Effects of Obesity on Lipid Metabolism, Ahmed H. Kissebah and Glenn R. Krakower. Part II: Noninsulin-Dependent Diabetes Mellitus. Genetics of Noninsulin-Dependent Diabetes Mellitus (NIDDM), Henning Beck-Nielsen, Allan Vaag, and Kirsten Ohm Kyvik. Insulin Secretion in Type II Diabetes Mellitus, Yogish C. Kudva and Peter C. Butler. Insulin Action and Insulin Resistance in Noninsulin-Dependent Diabetes Mellitus, John J. Nolan and Jerrold M. Olefsky. Dyslipidemia in Noninsulin-Dependent Diabetes Mellitus, Lisa A. Kosmiski and Robert H. Eckel. Exercise and Noninsulin-Dependent Diabetes Mellitus (NIDDM), Judith G. Regensteiner, Suzanne L. Brandenberg, and Jane E. B. Reusch. Glucose Toxicity and Insulin Resistance in NIDDM, Hannele Yki-Jarvinen. Energy Metabolism and Sympathetic Activity in Patients with Insulin Resistance, Luc Tappy and Nicolas Paquot. Effects of NIDDM on Vascular Tone Regulation, Alain D. Baron and Helmut O. Steinberg. Part III: Insights Gained from Other Insulin-Resistance Syndromes. Insulin Resistance in the Polycystic Ovary Syndrome, Andrea Dunaif and Carol Beth Book. Dietary Management of NIDDM, Frank Q. Nuttall and Mary C. Gannon. Hypertension and Insulin Resistance, Andrea Natali, Stefano Taddei, and Ele Ferrannini. Lessons Learned from Clinical and Basic Research Applied to the Study of Patients with Severe Insulin Resistance, David E. Moller and Heike Benecke. Treatment of Obesity Through Changes in Lifestyle, Rena R. Wing. Syndrome X: Past, Present, and Future, Gerald M. Reaven. Index.
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