Renal protective effect of ACE inhibition and angiotensin II blockade
Author(s)
Bibliographic Information
Renal protective effect of ACE inhibition and angiotensin II blockade
（Experimental nephrology, 4 /S1 /96）
S. Karger, 1996
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8 figures, 6 tables, 1996
Includes bibliographies and indexes.
Description and Table of Contents
Description
This timely issue reviews new therapeutic strategies for preventing or delaying renal disease progression. Special attention is given to pharmacologic interventions aimed at inhibiting the synthesis of angiotensin II or blocking its biological activity at the receptor level. The papers presented in this issue provide thorough coverage of the topic from the role of the renin-angiotensin system in the local control of renal function to the protective effects of ACE inhibitors in diabetes. Taken together, the studies document that, when urinary protein excretion is reduced by pharmacologic interventions, a proportional reduction in the rate of renal disease progression can be achieved. Clinical trials are now being carried out to investigate whether angiotensin II receptor blockade offers advantages compared to ACE inhibitors in slowing renal disease progression. All those wishing to learn about the latest advances will appreciate this valuable update.
Table of Contents
- The intrarenal renin-angiotensin system - a paracrine system for the local control of renal function separate from the systemic axis, R.C. Harris, H.-F. Cheng
- From converting enzyme inhibition to angiotensin LL receptor blockade - new insight on angiotensin II receptor subtypes in the kidney, G. Wolf, E.G. Neilson
- The renin-angiotensin system and renal function in transgenic (mRen2)27 rats, V. Gross et al
- Impact of renin-angiotensin system blockade on structure and function of glomerular membrane components in animal models of kidney disease, A. Remuzzi, E.I. Mohamed
- Mechanisms of injury in progressive renal disease, S. Anderson
- Renal effects of angiotensinLL receptor blockade and angiotensin-converting enzyme inhibition in healthy subjects, M. Bumier, H.R. Brunner
- Prognostic value of the short-term antiproteinuric response to ACE inhibition for prediction GFR decline in patients with non diabetic renal disease, F.H. Wapstra et al
- The renoprotective action of angiotensin-converting enzyme inhibitors in diabetes, P. Ruggenenti, G. Remuzzi.
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