Presenilins and Alzheimer's disease

著者

• Younkin, S. G. (Steven G.)
• Tanzi, Rudolph E.
• Christen, Yves

書誌事項

Presenilins and Alzheimer's disease

S.G. Younkin, R.E. Tanzi, Y. Christen (eds.)

（Research and perspectives in Alzheimer's disease）

Springer-Verlag, c1998

• hardcover

注記

Includes bibliographical references and index

内容説明・目次

内容説明

The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.

目次

Molecular Genetics of the Presenilins in Alzheimer's Disease.- Alzheimer's Disease: A Matter of Dominance.- Alternative Endoproteolysis of the Presenilins and Familial Alzheimer's Disease.- The APP and PS1/2 Mutations Linked to Early Onset Familial Alzheimer's Disease Increase the Extracellular Concentration of A?1-42(43).- Metabolism and Function of Presenilin 1.- Mechanistic Studies of the Effect of Presenilins 1 and 2 on APP Metabolism.- Presenilin 2 - APP Interactions.- The Cellular Biology of Presenilin Proteins and a Novel Mechanism of Amyloid ?-Peptide Generation.- Regulation of Presenilin 1 Phosphorylation and Transcriptional Activation of Signal Transduction-Induced Genes by Muscarinic Receptors.- Neuronal Regulation of Presenilin-1 Processing.- Transgenic Approaches to the Study of Alzheimer's Disease.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA47073715
• ISBN:
  • 3540639977
• LCCN: 97052014
• 出版国コード: gw
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Berlin ; New York
• ページ数/冊数: xv, 100 p.
• 大きさ: 24 cm
• 分類:
  • LCC : RC523
  • DC21 : 616.8/3107
• 件名:
  • LCSH : Alzheimer's disease -- Molecular aspects
  • LCSH : Alzheimer's disease -- Genetic aspects
  • LCSH : Presenilins
• 親書誌ID:
  • BA06823803