Response of different species to total body irradiation
著者
書誌事項
Response of different species to total body irradiation
(Series in radiology, 10)
Nijhoff , Distributors for the United States and Canada, Kluwer Academic Publishers, 1984
大学図書館所蔵 全3件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Based on a workshop organized by the Radiological Institute TNO and the Armed Forces Radiobiological Institute held at Rijswijk on July 1, 1983
Includes bibliographies and index
内容説明・目次
内容説明
J.J. Broerse, Radiobiological Institute TNO, Rijswijk, The Netherlands, and T .J. MacVittie, Armed Forces Radiobiology Research Institute, Bethesda, MD, USA. During the past decade, relatively few new studies have been initiated on the response of different species to high-dose, total-body irradia- tion. For information on the LDSO/30d (the dose which produces 50 percent lethality within 30 days), one is generally referred to the older literature (e. g., Bond, Fliedner and Archambeau, 1965). Compari- son of experimental data reveals considerable variations in LDSD values even after total-body irradiation with conventional X rays, ranging from 4 to 6 Gy in the monkey, 7.1 to 9 Gy in the rat and from 6.4 to 9 Gy in the mouse (see also Hall, 1978). Part of the discrepancy in the LDso values can possibly be attributed to inadequacies in the dosimetry procedures and exposure arrangements employed. As far as clinical experience is concerned, there is now an appreciable amount of information available about the effect of total- body irradiation as a conditioning treatment for bone marrow transplan- tation in patients suffering from leukaemia or aplastic anaemia.
The results from different centres, including the incidence of complications such as radiation pneumonitis, are considerably different. This can part I y be connected with the application of different radiation sched- ules: large single dose versus fractionated or protracted irradiation.
目次
Some practical aspects of dosimetry and dose specification for whole body irradiation.- Dose and cell-survival calculations in anthropomorphic phantoms.- Susceptibility to total body irradiation.- Acute lethality - the hemopoietic syndrome in different species.- Early radiation mortality and recovery in large animals and primates.- Acute lethality and radiosensitivity of the canine hemopoietic system to Cobalt-60 gamma and mixed neutron-gamma irradiation.- Surmary of the discussion on physical aspects and acute lethality in different species.- Survival patterns and hemopathological responses of dogs under continuous gamma irradiation.- Haematopoietic syndrome in pigs.- Occurrence of radiation syndromes in rodents and monkeys in dependence on dose rate and radiation quality.- The response of man to accidental irradiation.- Total body irradiation and LD50 in man.- Biological factors affecting the occurrence of radiation syndromes.- Surmary of discussions following presentations on marrow response and hemopoietic syndromes.- Surmary of round table discussion on response of different species.
「Nielsen BookData」 より