Protein kinase functions
著者
書誌事項
Protein kinase functions
（Frontiers in molecular biology, 29）
Oxford University Press, 2000
- : hbk
- : pbk
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注記
Includes bibliographical references and index
"The first edition of Protein kinases was published in the Frontiers in molecular biology series in 1994"--pref.
内容説明・目次
- 巻冊次
-
: pbk ISBN 9780199637706
内容説明
Since the publication of Protein Kinases in 1994 many novel protein kinases have been discovered, but perhaps more importantly there have been dramatic advances in our understanding of the cellular functions of this remarkably diverse class of proteins. Protein Kinase Functions is not just an update of the previous edition but provides a new focus on the context and function of protein kinases, thus reflecting the recent advances in kinase biology.
Chapters on genetic approaches to protein kinase functions, the MAP kinase pathway, and cyclin-dependent kinases have been completely updated and new topics covered in depth are: phosphatidylinositol 3-kinase signalling, JAK-STAT signalling, suppression of tyrosine kinases by the SOCS family proteins, the TGFss
superfamily, and the involvement of protein kinases in response to DNA damage. Throughout, emphasis is placed not on individual kinases, but on the functional aspects of the whole system and the relationship between processes and molecules. It is the aim of Protein Kinase Functions to enable the reader to assimilate, compare, and integrate the molecular machinery used by cells to co-ordinate and respond to their environments.
目次
- Phosphatidylinositol 3-kinase signalling: a tale of two kinase activities
- Mammalian MAP kinase pathways
- Genetic approaches to protein kinase function in lower eukaryotes
- Specificity in JAK-STAT signalling
- On the road to destruction: suppression of protein tyrosine kinase
- Cyclin-dependent protein kinases
- Mechanisms and biology of signalling by serine/threonine kinase receptors form the TGFss superfamily
- The ATM and DNA-PK proteins: The sensing, signaling and repair of DNA Damage
- 巻冊次
-
: hbk ISBN 9780199637713
内容説明
Since the publication of "Protein Kinases" in 1994 many novel protein kinases have been discovered, but perhaps more importantly there have been advances in our understanding of the cellular functions of this diverse class of proteins. This text is not just an update of the previous edition but provides a new focus on the context and function of protein kinases, thus reflecting the advances in kinase biology. Chapters on genetic approaches to protein kinase functions, the MAP kinase pathway, and cyclin-dependent kinases have been completely updated and new topics covered in depth are: phosphatidylinositol 3-kinase signalling, JAK-STAT signalling, suppression of tyrosine kinases by the SOCS family proteins, the TGFb superfamily, and the involvement of protein kinases in response to DNA damage. Throughout, emphasis is placed not on individual kinases, but on the functional aspects of the whole system and the relationship between processes and molecules. It aims to enable the reader to assimilate, compare, and integrate the molecular machinery used by cells to co-ordinate and respond to their environments.
目次
- Phosphatidylinositol 3-kinase signalling - tale of two kinase activities
- mammalian MAP kinase pathways
- genetic approaches to protein kinase function in lower eukaryotes
- specificity in JAK-STAT signalling
- on the road to destruction - suppression of protein tyrosine kinase
- cyclin-dependent protein kinases
- mechanisms and biology of signalling by serine/threonine kinase receptors from the TGFb superfamily
- the ATM and DNA-PK proteins - the sensing, signalling and repair of DNA damage.
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