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v. 50 ISBN 9783764358211
内容説明
Including details of current advances in drug research, this volume includes contributions by P.N. Kaul, M. Rohmer, T.D. Johnson, and R.W. Rockhold.
目次
- Drug discovery - past, present and future, P.N. Kaul
- isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs?, M. Rohner
- endothelium-derived hyperpolarizing factor - a critical appraisal, G. Edwards and A.H. Weston
- glutamatic involvement in psychomotor stimulant action, R.W. Rockhold
- the identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection, J.M. Colacino and K.A. Staschke
- polyamines and cerebal ischemia, T.D. Johnson.
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v. 51 ISBN 9783764358228
内容説明
This volume is part of a series of texts that contain reviews on a wide spectrum of topical areas in pharmaceutical and pharmacological research.
目次
- Development of HIV protease inhibitors - a survey, Shijun Ren and Eric J. Lien
- insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment - current status and therapeutic possibilities, Nicholas C. Turner and John C. Clapham
- peptide drug delivery into the central nervous system, Laszlo Prokai
- abnormalities of protein kinases in neurodegenerative diseases, Ravenska T.E. Wagey and Charles Krieger
- biomimicry as a basis for drug discovery, Vera M. Kolb
- serotonin in migraine - theories, animal models and emerging therapies, Kirk W. Johnson et al
- the application of high-throughput screening to novel lead discovery, Barry A. Kenny et al.
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v. 52 ISBN 9783764359799
内容説明
Founded in 1959, the series has moved from its initial focus on medicinal chemistry to a much wider scope. This volume encompasses all fields concerned with the development of therapeutic drugs, and the elucidation of their mechanisms of action. When combined with the other volumes, it serves as a time-saving source of information for researchers concerned with drug research, and all those who need to keep abreast of ongoing developments in medicines.
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v. 53 ISBN 9783764360283
内容説明
This text is part of a series which provides expert written reviews on a spectrum of areas in pharmaceutical and pharmacological research. Each volume contains fully cross-referencing indexes which link the books together, forming an encyclopaedic work.
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v. 54 ISBN 9783764361136
内容説明
This volume covers a range of topics including caco-2 cell permeability versus human gastrointestinal absorption - QSPR analysis; pharmacology of appetite supression; serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors; neuropeptides in drug research; regulation of NMDA receptors by ethanol; and troglitazone and emerging glitazones - new avenues for potential therapeutic benefits beyond glycemic control and applications of developmental biology to medicine and agriculture.
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v. 55 ISBN 9783764361938
内容説明
Progress in Drug Research is a prestigious book series which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmacological research. Founded in 1959 by its current editor, the series has moved from its initial focus on medicinal chemistry to a much wider scope. Today it encompasses all fields concerned with the development of new therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drug research. Invited authors present their biological, chemical, biochemical, physiological, immunological, pharmaceutical, toxicological, pharmacological and clinical expertise in carefully written reviews and provide the newcomer and the specialist alike with an up-to-date comprehensive list of prime references. Each volume of Progress in Drug Research contains fully cross-referencing indices which link the books together, forming a virtually encyclopaedic work.
The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.
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v. 56 ISBN 9783764362652
内容説明
Founded in 1959 by its current Editor, the series has moved from its initial focus on medicinal chemistry to a much wider scope. Today it encompasses all fields concerned with the development of new therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drug research. Invited authors present their biological, chemical, biochemical, physiological, immunological, pharmaceutical, toxicological, pharmacological and clinical expertise in carefully written reviews and provide the newcomer and the specialist alike with an up-to-date comprehensive list of prime references. Each volume of Progress in Drug Research contains fully cross-referencing indices which link the books together, forming a virtually encyclopaedic work. The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.
目次
Alternative medicine: Herbal drugs and their critical appraisal - Part I.- Current and potential therapies for the treatment of herpesvirus infections.- Quantitiative structure-activity relationships of antianginal drugs.- Purine analogs as CDK enzyme inhibitory agents: A survey and QSAR analysis.- Anti-influenza drugs and neuraminidase inhibitors.- Index Vol. 56.- Index of titles, Vol. 1-56.- Author and paper index, Vol. 1-56.
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v. 57 ISBN 9783764362669
内容説明
This text provides extensive expert-written reviews on a wide spectrum of topical areas in pharmaceutical and pharmacological research.
目次
Pushkar N. Kaul and Balawant S. Joshi Alternative medicine: herbal drugs and their critical appraisal - Part II E. Domingo, A. Mas, E. Yuste, N. Pariente, S. Sierra, M. Gutierrez-Rivas and L. Menendez-Arias Virus population dynamics, fitness variations and the control of viral disease: an update Doreen Ma Applications of yeast in drug discovery C.L. Kaul and P. Ramarao Sympathetic nervous system and experimental diabetes: role of adrenal medullary hormones Jay A. Glasel From outer to inner space: traveling along a scientific career from astrochemistry to drug research
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v. 58 ISBN 9783764366247
内容説明
Jay A. Glasel: Drugs, the human genome, and individual-based medicine.- Vera M. Kolb: Herbal medicine of Wisconsin Indians.- Paul L. Skatrud: The impact of multiple drug resistance (MDR) proteins on chemotherapy and drug discovery.- John W. Ford, Edward B. Stevens, J. Mark Treherne, Jeremy Packer and Mark Bushfield: Potassium channels: Gene family, therapeutic relevance, high-throughput screening technologies and drug discovery.- David T. Wong and Frank P. Bymaster: Dual serotonin and noradrenaline uptake inhibitor class of antidepressants - Potential for greater efficacy of just hype?.- Satya P. Gupta: Advances in QSAR studies of HIV-1 reverse transcriptase inhibitors
目次
Drugs, the human genome, and individual-based medicine.- Herbal medicine of Wisconsin Indians.- The impact of multiple drug resistance (MDR) proteins on chemotherapy and drug discovery.- Potassium channels: Gene family, therapeutic relevance, high-throughput screening technologies and drug discovery.- Dual serotonin and noradrenaline uptake inhibitor class of antidepressants - Potential for greater efficacy or just hype?.- Advances in QSAR studies of HIV-1 reverse transcriptase inhibitors.- Index Vol. 58.- Index of titles, Vol. 1-58.- Author and paper index, Vol. 1-58.
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v. 59 ISBN 9783764366254
内容説明
Nikolaus Seiler, Benoit Duranton and Francis Raul: The polyamine oxidase inactivator MDL 72527.- Zhi Hong and Craig E. Cameron: Pleiotropic mechanisms of ribavirin antiviral activities.- Jie Hong Hu and Charles Krieger: Protein phosphorylation networks in motor neuron death.- James O. Schenk: The functioning neuronal transporter for dopamine: kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate.- Laszlo Prokai: Central nervous system effects of thyrotropin-releasing hormone and ist analogues: opportunities and perspectives for drug discovery and development.- David F. Horrobin: A new category of psychotropic drugs: neuroactive lipids as exemplified by ethyl eicosapentaenoate (E-E).- Suprabhat Ray, Reema Rastogi and Atul Kumar: Current status of estrogen receptors
目次
Nikolaus Seiler, Benoit Duranton and Francis Raul: The polyamine oxidase inactivator MDL 72527.- Zhi Hong and Craig E. Cameron: Pleiotropic mechanisms of ribavirin antiviral activities.- Jie Hong Hu and Charles Krieger: Protein phosphorylation networks in motor neuron death.- James O. Schenk: The functioning neuronal transporter for dopamine: kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate.- Laszlo Prokai: Central nervous system effects of thyrotropin-releasing hormone and ist analogues: opportunities and perspectives for drug discovery and development.- David F. Horrobin: A new category of psychotropic drugs: neuroactive lipids as exemplified by ethyl eicosapentaenoate (E-E).- Suprabhat Ray, Reema Rastogi and Atul Kumar: Current status of estrogen receptors.- Index Vol. 59.- Index of titles, Vol. 1-59.- Author and paper index, Vol. 1-59
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Special topic ISBN 9783764369262
内容説明
This second volume of PDR SPECIAL TOPICS contains five review articles, covering nearly the entire field of fungal diseases in humans as well as therapeutic approaches. The main emphasis of the book lies in antifungal therapy: the most relevant information on the present state of the art of antifungal chemotherapy for dermatomycoses, subcutaneous and invasive mycoses is summarized, and open questions and unsolved problems are presented. The book is ideal for both the practitioner as well as advanced student.
目次
Classification and taxonomy of fungi pathogenic for warm-blooded hosts.- Fungal diseases.- Diagnosis of fungal diseases.- Antifungal therapy - state of the art at the beginning of the 21st century.- Susceptibility testing of fungi - current status and open questions.
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v. 60 ISBN 9783764369873
内容説明
Progress in Drug Research is a prestigious book series which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmacological research. It serves as an important source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.
目次
Chemical and pharmacological investigations of Epimedium species: A survey.- Potential of p38MAP kinase inhibitors in the treatment of cancer.- Therapeutic role of peroxisome proliferator-activated receptors in obesity, diabetes and inflammation.- Quasispecies and the development of new antiviral strategies.- Maximizing the value of genomics in the drug discovery and development process.- Quantitative structure-activity relationships of carbonic anhydrase inhibitors.- Crystallins, genes and cataract.- Current and potential therapies for the treatment of herpesvirus infections.- Index Vol. 60.- Index of titles, Vol. 1-60.- Index and paper index, Vol. 1-60.
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