Protein lipidation
著者
書誌事項
Protein lipidation
(The enzymes / edited by Paul D. Boyer, Edwin G. Krebs, v. 21)
Academic Press, c2001
3rd ed
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented.
目次
Mechanism of Catalysis by Protein Farnesyltransferase
Structure of Protein Farnesyltransferase
Mutational Analyses of Protein Farnesyltransferase
Farnesyltransferase Inhibitors
Protein Geranylgeranyltransferase Type I
Biochemistry of Rab Geranylgeranyltransferase
Postisoprenylation Protein Processing: CXXX (CaaX) Endoproteases and Isoprenylcysteine Carboxyl Methyltransferase
Reversible Modification of Proteins with Thioester-Linked Fatty Acids
Biology and Enzymology of Protein N-Myristoylation
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