Gaba in the nervous system : the view at fifty years

Bibliographic Information

Gaba in the nervous system : the view at fifty years

editors, David L. Martin, Richard W. Olsen

Lippincott Williams & Wilkins, c2000

Available at  / 7 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

GABA in the Nervous System summarizes recent advances in understanding the role of GABA as a neurotransmitter. First discovered as an inhibitory signal in 1950, GABA may also fulfill a decisive role in diseases such as Parkinson's and Alzheimer's, stroke, and other clinical problems. This book provides a comprehensive understanding of GABA at both the molecular and systemic level. Each chapter provides a balanced view of current knowledge while referencing historical discoveries during the last half-century

Table of Contents

  • Adventures with GABA:Fifty Years On
  • Mechanisms Controlling GABA Synthesis and Degradation in the Brain
  • Cytoplasmic Membrane Transporters for GABA
  • Uptake and Storage of GABA in Synaptic Vesicles
  • GABA Chemistry:Analogs of GABA as Therapeutic and Investigational Agents
  • Function of GABA Receptors:Insights from Mutant and Knockout Mice
  • The Benzodiazepine Site of GABA Receptors
  • Pharmacologic Subtypes of GABA Receptors Based on Subunit Composition
  • Functional Domains of GABA Receptors
  • Kinetic Properties of GABA Receptor Channels
  • Alcohol and General Anesthetic Actions on the GABA Receptor
  • Regulation of GABA Receptors by Protein Phosphorylation
  • Neurosteroids and GABA Receptor Plasticity
  • GABA Receptors:Structure and Function
  • GABA Emerges as a Developmental Signal during Neurogenesis of the Rat Central Nervous System
  • GABA in the Basal Ganglia
  • Epilepsy
  • GABAergic Interneuronal Networks in the Hippocampus
  • GABA Neurons of the Hippocampal Formation:Localization, Vulnerability, and Plasticity
  • GABA Neurons of the Neocortex
  • GABA Receptor Diversity:A View from the Cerebellum
  • GABAergic Inhibition in the Cerebellar System
  • Neuromodulation of GABA in Developing and Mature Hypothalamic Neurons
  • GABA in the Mammalian Spinal Cord
  • GABA in the Retina
  • The Role of Glutamic Acid Decarboxylase and GABA in the Pancreas and Diabetes
  • Index

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