Axonal regeneration in the central nervous system
著者
書誌事項
Axonal regeneration in the central nervous system
（Neurological disease and therapy, v. 52）
Marcel Dekker, c2001
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Summarizing a review of research into factors that regulate, stimulate, and prevent regeneration in the central nervous system (CNS), this comprehensive reference progresses further into answering and resolving neuron capacity for axon regeneration in the mammalian CNS.
Axonal Regeneration in the Central Nervous System
analyzes axonal regeneration, reinnervation, and functional recovery in lower vertebrates
examines the correlation between developmental age and the ability to regenerate
considers mammalian neuron responses at the cell body, site of injury, and in the distal nerve, including apoptic cell death, and inflammatory and glial responses to injury
reviews genomic responses to axotomy with a comparative description of transcribed genes from successfully regenerating neurons and neurons incapable of regrowth
discusses how growing axons may induce the expression of genes in glia/Schwann cells following axotomy and regeneration
describes the use of gene therapy to deliver trophic and survival factors to injured neurons
explores the hospitable environments of the peripheral nerve, olfactory ensheathing cells, and fetal cell transplants for regeneration
discusses results from applications of fetal CNS tissue to human spinal cord injuries
and much more!
目次
Axon Regeneration in Lower Vertebrates
Molecular Determinants of Retinal Axon Pathfinding in Fish,
C. Stuermer and C. Leppert
Axonal Regeneration in the Primary Visual Pathway of Goldfish and Rats,
L. Benowitz, S. Leon, R. Tabibiazar, Y. Jing and N. Irwin
Regeneration of Axons in the CNS of Amphibians and Reptiles,
L. Beazley
Axonal and Synaptic Regeneration by Salamander Photoreceptors,
E. Townes-Anderson and M. Nachman-Clewner
Regeneration as a Function of Developmental Age
Cues from Developmental Models of Spinal Cord Regeneration for the Repair of the Injured Adult CNS,
J. D. Steeves
Intrinsic Control of Regeneration and the Loss of Regenerative Ability in Development,
J. Fawcett
Regeneration Following Axotomy of Mammalian Neurons
The Cell Body Response to Axotomy
Apoptotic Cell Death Following Axotomy,
P. Chaudhary and S. C. Sharma
Gene Expression in Axotomized Neurons: Identifying the Intrinsic Determinants of Axonal Growth,
K. J. L. Fernandes and W. Tetzlaff
A-Fiber Central Sprouting After Peripheral Nerve Injury - New Pathways for Pain?,
R. J. Mannion and C. J. Woolf
Response at the Site of Injury and in Degenerating/Regenerating Nerves
Inflammatory Response Following Nerve Injury,
G. Raivich and G. W. Kreutzberg
Glial Response to Injury,
S. Hirsch and M. Bahr
Axonal Sealing Following Injury,
G. D. Bittner and H. M. Fishman
N-Terminal Arginylation of Proteins and Transcellular Transfer of Small Molecules in Regenerating Nerves,
N. Ingoglia and N. Zhang
Gene Expression in Degenerating/Regenerating Nerves,
C. Gillen
Factors that Influence Axonal Outgrowth
Inhibition of Axonal Growth by the Myelin-Associated Inhibitory Proteins NI-35/NI-250/Nogo-A
M. E. Schwab
Inhibition of Axonal Growth by Myelin Associated Glycoprotein,
S. David and L. McKerracher
Axonal Growth in a Glial Environment,
G. Raisman
Cell Surface and Extracellular Molecules that Promote or Inhibit Axonal Growth,
M. Grumet
Strategies for Stimulating Axonal Growth Following CNS Injury
Neuroprotection from Cell Death Following Axotomy,
B. T. Himes and A. Tessler
The Use of Peripheral Nerve Transplants to Enhance Axonal Regeneration in CNS Neurons,
K. F. So and H.K. Yip
Transplantation of Schwann Cells and Ensheathing Glia to Improve Regeneration in Adult Spinal Cord,
G. Plant, A. Ramon-Cueto, and M. B. Bunge
Gene Therapy Strategies,
I. Fischer and Y.Liu
Spinal Cord Injury and Fetal CNS Tissue Transplantation: An Initial Bench-to-Bedside Translational Research Experience,
P. J. Reier, F. J. Thompson, R. G. Fessler, D. K. Anderson, and E. D. Wirth III
Therapies to Promote CNS Repair,
M. Murray
Perspective
Treatment of Degenerative Disorders of the Nervous System: from Helpless Descriptive Categorization to Rational Therapeutic Approaches,
H. Thoenen
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