Taurine and excitable tissues
著者
書誌事項
Taurine and excitable tissues
（Advances in experimental medicine and biology, 483 . Taurine ; 4）
Kluwer Academic/Plenum Publishers, c2000
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Taurine 4
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注記
"Proceedings of the International Taurine Symposium '99, an official Satellite Symposium of the 17th Biennial Meeting of the International Society for Neurochemistry, held August 3-8, 1999, in Siena, Italy"--T.p. verso
Includes bibliographical references and index
内容説明・目次
内容説明
Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the "setpoint" andcorresponds to values between 0.3-3M. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .
目次
- Keynote presentation. Appreciations. Plenary presentations. Part 1: Basic aspects and peripheral actions of taurine. 1. Post-transcriptional regulation of cysteine dioxygenase in rat liver
- D.L. Bella, et al. 2. The mitochondrial permeability transition and taurine
- M. Palmi, et al. 3. Cloning and characterization of the promotor region of the rat taurine transporter (TAUT) gene
- X. Han, et al. 4. Taurine prevents ischemia damage in cultured neonatal rat cardiomyocytes
- K. Takahashi, et al. 5. Effects of taurine and thiosulfate on the spectrophotometric properties of RNA and DNA
- S.I. Baskin, et al. 6. Ionomycin restores taurine transporter activity in cyclosporin-A treated macrophages
- H.W. Kim, et al. Part 2: Metabolic and nutritional aspects. 7. Daily dietary taurine intake in Japan
- E. Kibayashi, et al. 8. Comparative studies on serum taurine and plasma fatty acids in human between the sea side area in Toyama, Japan and the mountain areas in inner Mongolia, China
- E. Kibayashi, et al. 9. Biochemical and ultrastructural alterations in rat after hyperoxic treatment: Effect of taurine and hypotaurine
- G. Pitari, et al. 10. Hypotaurine protection on cell damage by singlet oxygen
- G. Pitari, et al. 11. Hypotaurine and superoxide dismutase: Protection of the enzyme against inactivation by hydrogen peroxide and peroxidation to taurine
- L. Pecci, et al. 12. Dietary taurine changes ascorbic acid metabolism and cholesterol metabolism in rats fed diets containing polychlorinated biphenyls
- H. Yokogoshi, et al. 13. Effects of long-term treatment with taurine in mice fed a high-fat diet: Improvement in cholesterol metabolism and vascular lipid accumulation by taurine
- S. Murakami, et al. 14. Hypolipidemie effect of taurine in golden syrian hamsters
- T. Takenaga, et al. 15. Taurine reduced atherosclerotic lesion development in apolipoprotein-E deficient mice
- Y. Kondo, et al. 16. Does taurine play an osmolarity role during ethanol intoxication? F. Lallemand, et al. Part 3: Taurine in the CNS. 17. Osmotic sensitivity of taurine release from hippocampal neuronal and glial cells
- J.E. Olson, G. Li. 18. Isovolumic regulation in nervous tissue: A novel mechanism of cell volume regulation
- O. Quesada, et al. 19. New role of taurine as an osmomediator between glial cells and neurons in the rat supraoptic nucleus
- N. Hussy, et al. 20. Gene expression of taurine transporter and taurine biosynthetic enzymes in hyperosmotic states: A comparative study with the expression of the genes involved in the accumulation of other osmolytes
- M. Bitoun, M. Tappaz. 21. Involvement of ion channels in ischemia-induced taurine release in the mouse hippocampus
- P. Saransaari, S.S. Oja. 22. Modulation of taurine release by metabotropic receptors in the developing hippocampus
- P. Saransaari, S.S. Oja. 23. Extracellular taurine as a parameter to monitor cerebral insults `on-line': Time courses and mechanisms as studied in vivo
- D.K. Scheller. 24. Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: A structure-activity relationship study
- M. Frosini, et al. 25. Taurine-induced synap
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