Renal cell carcinoma : molecular biology, immunology, and clinical management

Bibliographic Information

Renal cell carcinoma : molecular biology, immunology, and clinical management

edited by Ronald M. Bukowski and Andrew C. Novick

(Current clinical oncology, 4)

Humana Press, c2000

Available at  / 6 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

Leading clinicians and researchers critically survey a decade of clinical, biological, and pathological knowledge, and show how it is best applied to the management of both localized and advanced renal cell carcinoma. Their discussions include the latest developments in molecular genetics and immune dysfunction, and fully treat the roles of partial nephrectomy, radical nephrectomy, and laparoscopy. Also discussed are screening for renal cell carcinoma, diagnosis and staging, paraneoplastic syndromes, and prognostic factors in metastatic disease. The physicians further explore novel therapeutic aspects including the use of interferon, Interleukin-2, therapy for metastatic renal cell carcinoma, monoclonal antibody therapies, and antiangiogenic treatments to name a few. Summarizing a decade of scientific and therapeutic innovation, Renal Cell Carcinoma offers all physicians and clinical investigators treating kidney cancer today's gold-standard compendium of practical knowledge about the nature, diagnosis, and treatment of this difficult disease.

Table of Contents

Part I. Introduction. The Epidemiology of Renal Cell Carcinoma, Joshua E. Muscat. The Pathology of Renal Neoplasms, Howard S. Levin and Jonathan L. Myles. Immunologic Response to Renal Cell Carcinoma, James H. Finke, Lisa Salvucci Kierstead, Elena Ranieri, and Walter J. Storkus. Molecular Mechanisms of Immune Dysfunction in Renal Cell Carcinoma, Robert G. Uzzo, Patricia Rayman, Andrew C. Novick, Ronald M. Bukowski, and James H. Finke. Molecular Genetics of Renal Cell Carcinoma, Erik Enquist, Norman Zambrano, Burton Zbar, W. Marston Linehan, and McClellan M. Walther. Screening for Renal Cell Carcinoma, Evan B. Cohn and Steven C. Campbell. Renal Cell Carcinoma: Diagnosis and Staging, Joel W. Slaton and David A. Swanson. Paraneoplastic Syndromes in Renal Cell Carcinoma, Riyadh Aldaabil and David Peereboom. Prognostic Factors in Metastatic Renal Cell Carcinoma, Paul J. Elson. Part II. Management of Localized Renal Cell Carcinoma. Radical Nephrectomy and Nephron-Sparing Surgery for Localized Renal Cell Carcinoma, Andrew C. Novick. Management of Patients with Renal Cell Carcinoma and Vena Caval Thrombi, Chad W. M. Ritenour and Fray F. Marshall. Laparoscopic Surgery for Renal Cell Carcinoma, Inderbir S. Gill. Adjuvant Therapy for Renal Cell Carcinoma, Ronald M. Bukowski. Part III. Management of Advanced and/or Metastatic Renal Cell Carcinoma. The Role of Nephrectomy and Metastasectomy for Advanced Renal Cell Carcinoma, Robert G. Uzzo and Andrew C. Novick. Management of Pulmonary Metastases in Renal Cell Carcinoma Patients, Thomas W. Rice. Management of Skeletal Metastases in Renal Cell Carcinoma Patients, Michael J. Joyce. Management of Central Nervous System Metastases in Renal Cell Carcinoma Patients, John H. Suh and Gene H. Barnett. Chemotherapy for Metastatic Renal Cell Carcinoma (RCC), Javier A. Ruiz, Haralambos Raftopoulos, and Daniel P. Petrylak. Interleukin-2 in Metastatic Renal Cell Carcinoma, Thomas Olencki and Ronald M. Bukowski. Role of Interferon in Metastatic Renal Cell Carcinoma, Robert J. Motzer and William J. Berg. Combination Therapy for Treatment of Advanced Renal Cell Carcinoma, Jens Atzpodien, J. Janssen, J. Buer, S. Sel, and K. Oevermann. Monoclonal Antibodies in Advanced Renal Cell Carcinoma, Egbert Oosterwijk, Chaitanya R. Divgi, Martijn S. Steffens, and Neil H. Bander. Adoptive Immunotherapy in Renal Cell Carcinoma, Barbara J. Gitlitz, Arie S. Belldegrun, and Robert A. Figlin. Antiangiogenic Agents and Strategies in Renal Cell Carcinoma, Kevin R. Bigelow, Michael T. Spiotto, and Walter M. Stadler. Therapy for Patients with Uncommon Histologic Varieties of Renal Cell Carcinoma, Robert J. Amato. Palliation in Patients with Advanced Renal Cell Carcinoma: The Interface with Antineoplastic Therapy, Donna S. Zhukovsky. Index.

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