In vitro toxicology
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書誌事項
In vitro toxicology
Taylor & Francis, 2000
2nd ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity.
目次
1. Introduction S. Gad 2. General Principles for In Vitro Toxicology S. Gad 3. Ocular Toxicity Assessment In Vitro Toxicology J. Sina 4. In Vitro Methods to Predict Dermal Toxicology Ai-Lean Chew and Howard Maibach 5. Lethality Testing S. Gad 6. Mutagenicity/genotoxicity Anne Mitchell 7. Pyrogenicity and Muscle Irritation S. Gad 8. In Vitro Assays for Development Toxicity Elaine Faustman 9. Neurotoxicology In Vitro S. Gad 10. In Vitro Assessment of Nephrotoxicity Robin Goldstein 11.
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