Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linkted proteins

著者

書誌事項

Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linkted proteins

edited by Neal S. Young, Joel Moss

Academic Press, c2000

タイトル別名

PNH and the GPI-linked proteins

PNH and the GPI-linked proteins

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内容説明・目次

内容説明

Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients. Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins. This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins.

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詳細情報

  • NII書誌ID(NCID)
    BA51217794
  • ISBN
    • 0127729402
  • LCCN
    99065876
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    San Diago
  • ページ数/冊数
    xiii, 279 p.
  • 大きさ
    26 cm
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