Modern visualisation of the endothelium
Author(s)
Bibliographic Information
Modern visualisation of the endothelium
(Endothelial cell research series)
Harwood Academic, c1998
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and index
Description and Table of Contents
Description
There can no longer be any doubt that the endothelium represents a very active tissue and is not, as had previously been thought, merely an inert lining material. On the contrary, the endothelium exerts a powerful influence on its environs through the release of multiple regulatory factors such as nitric oxide, endothelium derived hyperpolarizing factor and endothelin. It is therefore crucial to our understanding of the cardiovascular system that we are able to visualize the endothelial layer at the molecular level. Quantitative morphological studies permit visualization at this level, allowing the assessment of the changes that occur in the disease state. Modern methods of computerized image analysis have been applied to reconstruct the endothelial layer in three-dimensions - detecting even the most subtle of changes.
Within these covers, an integrated text has been gathered by experts in each of their fields. They detail the latest technical and conceptual advances in the visualization of endothelium, its production of regulatory molecules and pathological changes.
Table of Contents
1. The Endothelium: Electron-Immunocytochemistry of Vasoactive Agents 2. Localization of Chemical Mediators in the Endothelium 3. Neurovascular Interactions 4. Endothelium and Matrix Interactions 5. Modulation of Secretion of von Willebrand Factor from Endothelial Cells 6. In Vivo Imaging: Correlation with Morphology 7. Quantifying and Imaging Activated Endothelium in Inflammation 8. Targeted Gene Manipulation and Gene Transfer to Study Vascular Biology 9. The Renin Angiotensin System, The Endothelium and Vascular Diseases
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