Neuro-immune interactions in neurologic and psychiatric disorders
Author(s)
Bibliographic Information
Neuro-immune interactions in neurologic and psychiatric disorders
(Research and perspectives in neurosciences)
Springer, c2000
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
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  United States of America
Note
Includes bibliographical references and index
Description and Table of Contents
Description
The idea that the brain is an "immune-privileged site" has perhaps served to slow our realization that the intact brain can generate its own inflammatory reactions. These responses can be to peripheral infection, or they can arise from local, internal causes, for instance as a response to stress or to the se- vere changes in neuronal activity in seizure or the loss of oxygen in stroke. We are also becoming increasingly aware of the contribution of local inflam- matory reactions to certain neurodegenerative diseases such as Alzheimer's In fact, evidence is accumulating that inflammatory processes disease (AD). contribute to the progression of AD, suggesting the possibility of using cur- rently available or novel anti-inflammatory agents to interfere with this terri- ble disease. Correlations are also being made between inflammatory signs and mental illness, which is a new frontier of research. This book presents the current state of knowledge in a variety of areas relevant to neuro-immune interactions, with particular attention to AD.
Table of Contents
Organization of inflammatory processes in Alzheimers disease.-Glial cytokines in neurodegenerative conditions.-Contributions of the glial injury response to the multifactorial pathogenesis of Alzheimer's Disease.-Cytokine communication between neurons and glia and the pathogenesis of Alzheimer's disease.-Glial hyperactivity during aging as a neuroinflammatory process.-Mechanistic and metaphorical connections between NF-kB and the secreted Alzheimer's ss-amyloid precursor protein.-Pathological and biochemical studies of chronic neuroinflammation may lead to therapies for Alzheimer's disease.-Serotonine-immune interactions in major depression.-Responses in the Raphe-hippocampal serotonergic system during peripheral inflammation: Putative role in sickness behaviour.-Neuronal control of the immune response in the central nervous system: From pathogenesis to therapy.- And other contributions
by "Nielsen BookData"