Molecular aspects of anticancer drug-DNA interactions
著者
書誌事項
Molecular aspects of anticancer drug-DNA interactions
（Topics in molecular and structural biology）
CRC Press, 1993-
- v. 1
- v. 2
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
目次
Selectivity in Alkylating Agent-DNA Interactions. Structure-Activity Studies of Anthracycline-DNA Complexes. Advances in the Study of Pyrrolo[2,1-c][1,4] Benzodiazepine (PBD) Antitumour Antibiotics. Molecular Aspects of the Interaction of (+)-CC-1065 with DNA. Molecular Aspects of Platinum-DNA Interactions. New Platinum Drugs. Echinomycin and Related Quinoxaline Antibiotics. Molecular Basis of Neocarzinostatin Action: Roles of DNA Microstructure and Thiol in the Mechanism of Bistranded Oxidative Damage. Antisense Oligonucleotides as Potential Inhibitors of Gene Expression. Antigene Nucleic Acids-Inhibition of Gene Expression Via Triple Helix Formation. Design of Sequence-Specific Agents: Lexitropsins. Index.
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