Frontiers in biomedical polymer applications

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Bibliographic Information

Frontiers in biomedical polymer applications

edited by Ralphael M. Ottenbrite ; associate editors, Emo Chiellini ... [et al.]

Technomic Pub., c1998-

  • v. 2

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Note

An accumulation of the papers presented at the First International Meeting on the Frontiers of Medical Application of Polymers, held in St. Margarite, Italy

Includes bibliographical references and index

Description and Table of Contents

Volume

ISBN 9781566765770

Description

The use of polymers in medicine has become a reality over the last 10 years. Scientists have been attempting to develop biomimetic materials to substitute for flawed or damaged natural systems. This new book presents the most up-to-date developments in the use of synthetic polymers as biomaterials. Frontiers in Biomedical Polymer Applications is a compilation of the papers presented at the first International Meeting on the Frontiers of Medical Applications of Polymers. Held in St. Margarite, Italy, participants from countries throughout the world came to present their findings and to discuss future directions in this rapidly growing field. The text contains all 24 of the presentations and is well-illustrated with over 200 figures, tables, formulas and schemes. Frontiers in Biomedical Polymer Applications is required reading for anyone interested in the current developments in polymers as bioapplications, as well as implant materials, polymeric drugs and drug delivery systems. Keep pace with the latest developments in biomedical polymer applications.

Table of Contents

Preface Surface Modification of Colloidal Drug Carriers (Martin Malmsten) Hybrid Polymeric Hydrogels for the Controlled Release of Protein Drugs: DSC Investigation of Water Structure (E. E. Chiellini, D. Giannasi, R. Solaro, E. Chiellini and E. Grillo Fernandes) Degradable Polyphosphazenes for Biomedical Applications (Etienne Schacht, Joke Vandorpe, Yahia Lemmouchi, Stephane Dejardin and Leonard Seymour) Reorganization of Fibronectin by Fibroblasts and Signaling via Integrins Are Related to the Biocompatibility of Materials (Thomas Groth and Georgi Altankov) Self-Assemblies as Drug Delivery Systems (Mamoru Haratake, Ruifeng Zhao, Jun Liao and Raphael M. Ottenbrite) Effective Reconstitution of Cell Membrane Proteins into Liposome (Junzo Sunamoto) Characterization of Vesicles for Vascular Cell Targeting: Influence of Dextran Coating (Maud Seras-Cansell, Hamid Sahli, Vincent Dubois, Didier Letourneur and Jacqueline Jozefonvicz) Intelligent Polymer Systems for Molecular Separation and Controlled Delivery of Drugs (Mario Casolaro) Cytocompability of a Polyelectrolyte Complex and of Its Thermal Condensation Products (R. Sbarbati-Delguerra, G. D. Guerra, M. Tricoli, P. Cerrai and S. Maltini) Inclusion Complexes of Antihypertensive Drugs with New Modified ?-Cyclodextrins (M. C. Breschi, E. Chiellini, F. Morganti and R. Solaro) Poly(Ether-Amidoamines) versus Polyamidoamines: Chemico-Physical Characterization and Cytotoxicity (M. C. Tanzi, P. Petrini, M. Moscatelli and G. Garlaschelli) Different Sulfation Degree of Hyaluronic Acid as Heparin-Like Molecule: Physico-Chemical Characterization and Biological Performance (Rolando Barbucci, Filippo Venturi and Antonietta Albanese) Complexes of Copper(II) with Glycosaminoglycans and Their Biological Activity (Agnese Magnani, Stefania Lamponi and Rolando Barbucci) Synthesis of Bioabsorbable Polyester, Polydepsipeptide with Function-alized Side-Chain Groups, and Their Utilization as Drug Carriers (Tatsuro Ouchi) Affinity-Binding of Cells to Sephadex Derivatized with Peptides and Proteins (G. A. J. Besselink, T. Beugeling and A. Banties) Polymeric Membranes for Hybrid Liver Support Devices: The Effect of Membrane Morphology on Hepatocyte Viability and Functions (C. Catapno, M. C. Di Lorenzo, L. De Bartolo, C. Della Volpe, C. Migliaresi and F. Menichini) Immobilization of Plasminogen onto Polyurethane Surfaces (W. Marconi, A. Piozzi and D. Romoli) Comparative Evaluation of PMMA Intraocular Lenses (C. Della Volpe, L. Fambri, C. Migliaresi and M. De Concini) Impact Behavior of UHMWPE/HA Composites for Orthopedic Prostheses (R. L. Reis, P. L. Granja and A. M. Cunha) Determination and Influence of Residual Metals in Poly (L-Lactide) (D. Cam, M. Marucci, M. Fadel and P. Goberti) Contribution of New Partially Biodegradable Composites to the Design of Reinforced Resorbable Implants for Surgery (Julio San Roman, Pedro Guillen and Antonio Lopez Bravo) Effect of Crystallization Temperature on the Structure of Amorphous Domain of Poly-L-Lactide (S. Iannace, L. Ambrosio and L. Nicolais) Poly(D,L-Lactide-CO-?-Caprolactone): Synthesis and Characterization (S. Aslan, L. Fambri, A. Guerriero and C. Migliaresi) Multi-Step Surface Tailoring of Poly(Ethylene Terephthalate) (D. Cohn and T. Stern) Index
Volume

v. 2 ISBN 9781566767149

Description

The use of polymers in medicine has become a reality over the last 10 years. Scientists have been attempting to develop biomimetic materials to substitute for flawed or damaged natural systems. This new book presents the most up-to-date developments in the use of synthetic polymers as biomaterials Frontiers in Biomedical Polymer Applications is a compilation of the papers presented at the first International Meeting on the Frontiers of Medical Applications of Polymers. Held in St. Margarite, Italy, participants from countries throughout the world came to present their findings and to discuss future directions in this rapidly growing field. The text contains all 24 of the presentations and is well-illustrated with over 200 figures, tables, formulas and schemes.

Table of Contents

Preface Polymers in Gene Therapy (Abraham J. Domb and Menashe Y. Levy) Stimuli-Responsive Polymers Grafted onto Polyacrylic Acid and Chitosan Backbones as Bioadhesive Carriers for Mucosal Drug Delivery (Allan S. Hoffman, Gouhua Chen, Xiangdong Wu, Zhongli Ding, James E. Matsuura and Wayne R. Gombotz) Modeling of the 3D Structure of IFN-a-k, Characterization of Its Surface Molecular Properties and Preliminary Evaluation of Its Interactions with b-Cyclodextrin Derivatives (Emo Chiellini, Elisabetta E. Chiellini, Federica Chiellini, Roberto Solaro, Jacopo Tomasi, Vladimir Frecer and Stanislaw Miertus) Interaction of Oligopeptides with Macromolecular Drugs (Ruifeng Zhao, Mamoru Haratake, Jun Liao and Raphael M. Ottenbrite) Transport Phenomena in Moderately Hydrophilic Polymers: Poly(3-hydroxybutyrate) (A. L. Iordanskii, A. V. Krivandin, O.V. Startzev, P. P. Kamaev and U. J. Hanggi) Block Copolymers of L-Lactide and Poly(ethylene glycol) as Potential Drug-Releasing Materials: A Preliminary Investigation (P. Cerrai, G. D. Guerra, M. Tricoli, C. Cristallini and S. Maltini) Crosslinking Guar with Glutaraldehyde: A New Method of Preparing Hydrogels for Colon-Specific Drug Delivery (Irit Gliko-Kabir, Boris Yagen, Abraham Rubinstein and Adel Penhasi) Enhanced Radiation Sensitivity of Rat UMR 106 Osteogenic Sarcoma Tumors by PEGylated Bovine Hemoglobin (Robert G. L. Shorr, Rita Linberg, Katherine Fitzpatrick, Mary Nucci and Kwang Nho) Heparin Encapsulated in Liposomes Inhibits Smooth Muscle Cell Growth in Vitro (Maud Cansell, Claire Parisel, Jacqueline Jozefonvicz and Didier Letourneur) The Influence of Semisynthetic Heparin-Like Molecules with Regioselective Varied Sulfate Groups Covalently Immobilized on Polymer Surfaces on Thrombocyte Adhesion (B. Huppertz, H. Baumann and R. Keller) The Influence of Functional Groups on Semisynthetic Heparin-Like Molecules on Binding to Vascular Endothelial Growth Factor (VEGF165) (H. Baumann, B. Huppertz, R. Sharon, S. Tessler and G. Neufeld) Surface Modified Bioresorbable Polymers for Blood Contact: Study of Haemocompatibility (H. Thelen, H. Bienert, R. Engisch, H. Thissen, D. Klee, H. Hoecker, K. Hoffmeister, J. Vom Dahl and P. Hanrath) Development of Microvascular Artificial Platelet Inert Blood Vessels, Basic Principles and Animal Experiments (H. Bauman, R. Keller and U. Baumann) Dynamic Compliance Measurements of Synthetic Biodegradable Grafts and Natural Blood Vessels (G. Hellener, D. Cohn and G. Marom) Influence of Residual Monomers and Metals on Poly D,L-(Lactide) Thermal Stability (D. Cam, B. Bracci and M. Marucci) Cellulose Phosphates as Biomaterials (Pedro L. Granja, Mario A. Barbosa, Laurent Pouysegu, Bernard de Jeso and Charles Baquey) Partially Absorbable Composites for Internal Bone Fracture Fixation (L. Fambri, R. Fenner and C. Migliaresi) Index

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