Biochemistry of signal transduction and regulation

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Bibliographic Information

Biochemistry of signal transduction and regulation

Gerhard Krauss ; translated by Nancy Schönbrunner and Julia Cooper

Wiley-VCH, 2001

2nd ed

  • : hbk
  • : pbk

Available at  / 9 libraries

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Includes bibliographical references and index

Description and Table of Contents

Volume

: hbk ISBN 9783527303779

Description

Now the updated second edition of this bestselling title is available as softcover! Intracellular signal transduction, regulation of cellular activities, tumor formation, apoptosis - how do they work? These questions have become a central topic in Biology and Biological Chemistry. The importance of this field is mirrored in the 1999 Nobel prize for Physiology that went to G. Blobel for his findings in protein transport regulation. Over the last decade there has been great progress in the understanding of the molecular basis of signal transduction, and many facts are now basic knowledge for every medicinal chemist, biochemist, and biologist. Since an integral description of cellular regulation and signal transduction is scarcely covered in textbooks, this book fills a real gap. Starting from the principles of gene regulation and regulation of enzyme activity, the topics of this book cover function, structure, and integral construction of signalling pathways plus a detailed description of the various types of carriers such as second messengers, protein kinases, and transmembrane receptors. Central cellular processes like cell cycle regulation, oncogenesis and apoptosis are discussed in light of the properties of the signalling molecules involved. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. This book is actually two books: Regulation and Signal Transduction.
Volume

: pbk ISBN 9783527303786

Description

Inntracellular signal transduction, regulation of cellular activities, tumour formation, apoptosis - how do they work? These questions have become a central topic in biology and biological chemistry. The importance of this field is mirrored in the 1999 Nobel prize for physiology that went to G. Blobel for his findings in protein transport regulation. Since 1990 there has been great progress in the understanding of the molecular basis of signal transduction, and many facts are now basic knowledge for every medicinal chemist, biochemist and biologist. Starting from the principles of gene regulation and regulation of enzyme activity, the topics of this book cover function, structure and integral construction of signalling pathways plus a detailed description of the various types of carriers such as second messengers, protein kinases and transmembrane receptors. Central cellular processes like cell cycle regulation, oncogenesis and apoptosis are discussed in the light of the properties of the signalling molecules involved. The author relates the observed biological phenomena to the underlying biochemical processes.

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