High-yield cell and molecular biology
著者
書誌事項
High-yield cell and molecular biology
(High-yield series)
Lippincott Williams & Wilkins, c1999
- : pbk
大学図書館所蔵 全6件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references
内容説明・目次
内容説明
"High-Yield Cell and Molecular Biology" gives you more of what you need to prepare you for the USMLE Step 1! The information found in this text provides a strong understanding of introductory undergraduate cell and molecular biology which serves as a valuable review resource for the board exam. As part of the "High-Yield" series, material is presented in a concise, uncluttered fashion. The sections cover information typically found in a second year molecular biology course such as chromosomal DNA, chromosome replication and DNA synthesis, molecular genetics, gene amplification, inherited diseases and molecular immunology. Well illustrated, this text provides students with a strong foundation to prepare them for more advanced work in cell and molecular biology. It also serves as a great source for course review.
目次
- Part 1 Packaging of chromosomal DNA: nucleic acids
- the human genome
- chromosomes
- genes
- chromatin. Part 2 Chromosome replication and DNA synthesis: replication fork
- telomere
- damage and repair of DNA
- clinical importance of DNA repair mechanisms. Part 3 Genetic recombination: general recombination
- site-specific recombination. Part 4 Transposable elements: mechanisms of transposition
- transposable elements and genetic variability. Part 5 Gene amplification: clinical considerations. Part 6 Recombinant DNA technology: restriction enzymes
- gel electrophoresis
- enzymatic method of DNA sequencing
- southern blotting and prenatal testing for sickle cell anaemia
- isolating a human gene with DNA cloning
- polymerase chain reaction (PCR)
- producing a protein from a cloned gene
- site-directed mutagenesis and transgenic animals. Part 7 Control of gene expression: mechanism of gene regulation
- structure of transcription factors and gene regulatory proteins
- clinical consideration - growth hormone deficiency and Pit-1 transcription factor
- the "lac" operon
- summary. Part 8 Protein synthesis: transcription
- converting an RNA transcription to mRNA
- translation
- clinical considerations. Part 9 The nucleolus
- organization of the nucleolus
- assembly of the ribosome
- ultrastructure of the nucleolus. Part 10 Mutations of the DNA sequence: silent mutations
- missense mutations
- nonsense mutations
- frameshift mutations
- translocation mutations
- RNA splicing mutations
- transposable element mutations
- trinucleotide repeat mutations. Part 11 Molecular genetics: polymorphisms
- linkage (coinheritance)
- population genetics. Part 12 Inherited diseases: autosomal dominant inheritance
- autosomal recessive inheritance
- x-linked recessive inheritance
- mitochondrial inheritance
- multifactorial inheritance
- table of inherited disorders. Part 13 Multifactorial inherited diseases: definition
- example - type 1 diabetes. Part 14 Proto-oncogenes, oncogenes and anti-oncogenes: definitions
- designations
- classification of oncogenes
- mechanism of action of the "ras" proto-oncogene
- anti-oncogenes (tumor-suppressor genes)
- molecular pathology of colorectal cancer. Part 15 The cell cycle: phases of the cell cycle
- control of the cell cycle
- stages of the M phase. Part 16 Homeotic genes and anterior-posterior body pattern formation: human homeotic genes. Part 17 Mitochondrial genes: gene products that are encoded by mitochondrial DNA (mrDNA)
- other mitochondrial proteins
- mitochondrial diseases. Part 18 Molecular immunology: the clonal selection theory
- the B lymphocyte (B cell)
- the T lymphocyte (T cell)
- clinical considerations. Part 19 Receptors and signal transduction: ion channel-linked receptors
- G-protein-linked receptors
- enzyme-linked receptors
- steroid hormone (intracellular) receptors
- receptor types
- nitric oxide (NO)
- receptor-mediated endocytosis.
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